1) Biomimética Viral. Bionanopartículas con propiedades de autoensamblado y responsividad controlada mediante el diseño e ingeniería de proteínas que imitan propiedades de cápsides virales.
2) Sistemas de entrega de ácidos nucleicos basados en péptidos y proteínas de diseño.
3) Biosensores genéticos basados en CRISPR-Cas para detección de patógenos.
4) Andamios moleculares de proteínas y ácidos nucleicos de diseño y su uso como biosensores, nanovacunas y materiales con propiedades bioactivas.

Publicaciones

1. Melissa D. Morales-Moreno, Erick G. Valdés-Galindo, Mariana M. Reza, Tatiana Fiordelisio, Jorge Peon, Armando Hernandez-Garcia*. Multiplex gRNAs Synergically Enhance Detection of SARS-CoV-2 by CRISPR-Cas12a. The CRISPR Journal, 6, 2, 116-126 (2023). Factor de Impacto: 4.32

2. David S Moreno-Gutierrez, Ximena del Toro-Ríos, Natalia J Martinez-Sulvaran, Mayra B Perez-Altamirano, Armando Hernandez-Garcia*. Programming the Cellular Uptake of Protein-Based Viromimetic Nanoparticles for Enhanced Delivery. Biomacomolecules, 24, 4, 1563-1573 (2023). Factor de Impacto: 6.97

3. Esley Torres-García, Raúl Pinto-Cámara, Alejandro Linares, Damián Martínez, Víctor Abonza, Eduardo Brito-Alarcón, Carlos Calcines-Cruz, Gustavo Valdés-Galindo, David Torres, Martina Jabloñski, Héctor H Torres-Martínez, José L Martínez, Haydee O Hernández, José P Ocelotl-Oviedo, Yasel Garcés, Marco Barchi, Rocco D’Antuono, Ana Bošković, Joseph G Dubrovsky, Alberto Darszon, Mariano G Buffone, Roberto Rodríguez Morales, Juan Manuel Rendon-Mancha, Christopher D Wood, Armando Hernández-García, Diego Krapf, Álvaro H Crevenna, Adán Guerrero. Extending resolution within a single imaging frame. Nature Communications, 13, 7452 (2022). Factor de Impacto: 17.7

4. Gloria A Suárez-Ortiz, Rodrigo Hernández-Correa, Melissa D Morales-Moreno, Rubén A Toscano, Maria Teresa Ramirez-Apan, Armando Hernandez-Garcia, Manuel Amézquita-Valencia, Daniela Araiza-Olivera. Diastereomeric Separation of Chiral fac-Tricarbonyl(iminopyridine) Rhenium(I) Complexes and Their Cytotoxicity Studies: Approach toward an Action Mechanism against Glioblastoma. J. Med. Chem. 2022, 65, 13, 9281–9294 (2022). Factor de Impacto: 8.039

5. René de Bruijn, Pieta Cornelia Martha Wielstra, Carlos Calcines-Cruz, Tom van Waveren, Armando Hernandez-Garcia, Paul van der Schoot. A kinetic model for the impact of packaging signal mimics on genome encapsulation. Biophysical Journal, 121(13), 2583-2599 (2022). Factor de Impacto: 4.033

6. Armando Hernandez-Garcia*, Melissa Morales, Gustavo Valdés, Pavel Jiménez, Andrea Quezada. Diagnostics of COVID–19 Based on CRISPR–Cas Coupled to Isothermal Amplification: A Comparative Analysis and Update. Diagnostics, 12(6), 1434 (2022). Factor de Impacto: 3.706

7. David S Moreno-Gutierrez, Jesús Cepeda-Cervantes, Luis Vaca, Armando Hernandez-Garcia*. An artificial virus-like triblock protein shows low in vivo humoral immune response and high stability. Materials Science & Engineering C, 129, 112348 (2021). Factor de Impacto: 7.328

8. Armando Hernandez-Garcia*. Strategies to Build Hybrid Protein–DNA Nanostructures. Nanomaterials, 11(5), 1332 (2021). Factor de Impacto: 5.08

9. Carlos Calcines-Cruz, Ilya J. Finkelstein, Armando Hernandez-Garcia*. CRISPR-guided programmable self-assembly of artificial virus-like nucleocapsids. Nano Letters, 21(7), 2752-2757 (2021). Factor de Impacto: 11.19

10. Rosa E Cárdenas-Guerra, David S Moreno-Gutierrez, Oscar de J Vargas-Dorantes, Bertha Espinoza, Armando Hernandez-Garcia*. Delivery of Antisense DNA into Pathogenic Parasite Trypanosoma cruzi Using Virus-Like Protein-Based Nanoparticles. Nucleic Acid Therapeutics, 30(6), 392-401 (2020). Factor de Impacto: 5.49

11. Eddie G. Sanchez-Rueda, Estefani Rodriguez-Cristobal, Claudia L. Moctezuma González, Armando Hernandez-Garcia* Protein-coated dsDNA nanostars with high structural rigidity and high enzymatic and thermal stability. Nanoscale. 11, 18604-18611 (2019). Factor de Impacto: 7.79

12. Lione Willems, Larissa van Westerveld, Stefan Roberts, Isaac Weitzhandler, Carlos Calcines Cruz, Armando Hernandez-Garcia, Ashutosh Chilkoti, Enrico Mastrobattista, John Van Der Oost, Renko de Vries. The nature of the amorphous hydrophilic block affects self-assembly of an artificial viral coat polypeptide. Biomacromolecules. 20(10), 3641-3647 (2019). Factor de Impacto: 6.99

13. Margherita Marchetti, Douwe Kamsma, Ernesto Cazares Vargas, Armando Hernandez-Garcia, Paul van der Schoot, Renko de Vries, Gijs JL Wuite, Wouter H Roos. Real-Time Assembly of Viruslike Nucleocapsids Elucidated at the Single-Particle Level. Nano letters 19(8), 5746-5753 (2019). Factor de Impacto: 11.19

14. Ernesto Cazares Vargas, Martien Cohen Stuart, Renko de Vries, Armando Hernandez-Garcia*. Template‐free self‐assembly of artificial de novo viral coat proteins into nanorods: effects of sequence, concentration, and temperature. Chemistry–A European Journal. 25(47), 11058-11065 (2019). Factor de Impacto: 5.24

15. Armando Hernandez‐Garcia, Zaida Álvarez, Dina Simkin, Ashwin Madhan, Eloise Pariset, Faifan Tantakitti, Oscar de J. Vargas‐Dorantes, Sungsoo S Lee, Evangelos Kiskinis, Samuel I Stupp. Peptide–siRNA Supramolecular Particles for Neural Cell Transfection. Advanced Science. 6(3): 1801458 (2019) Factor de Impacto 16.81

16. A. Hernandez-Garcia*, M. A. Cohen Stuart, R. de Vries. Templated co-assembly into nanorods of polyanions and artificial virus capsid proteins. Soft Matter. 14, 132-139 (2018). Factor de Impacto 3.68

17. M. Santos Rocha, I. M. Storm, R. F. Bazoni, É. Ramos, A. Hernandez-Garcia, M. A. Cohen Stuart, F. Leermakers, R. de Vries. Force and Scale Dependence of the Elasticity of Self-Assembled DNA Bottle Brushes. Macromolecules. 51(1), 204-212 (2018). Factor de Impacto 5.98

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx