Acceso a usuarios
Bienvenid@

Tutores

ISMAEL BUSTOS JAIMES

Facultad de Medicina (FM)

Contacto

Teléfono: 55 56 23 22 60
Email: ismaelb@unam.mx
Sitio web: Visitar sitio web

Campos de conocimiento

Biofísica
Bioquímica
Biotecnología
Reconocimiento Molecular y Bioestructura

Líneas de investigación

Ensamble supramolecular de cápsides virales y otros nanocompartimentos de proteína para aplicaciones tecnológicas. Comunicación entre subunidades proteicas y transiciones alostéricas. Biocatálisis.

Publicaciones

- Sánchez-Moguel, I., Montiel, C., Bustos-Jaimes, I.* (2023). Therapeutic potential of engineered virus-like particles of Parvovirus B19. Pathogens 12, 1007. IF=3.70

- Marcos-Viquez, J., Rodríguez-Hernández, A., Álvarez-Añorve, L.I., Medina-García, A., Plumbridge, J., Calcagno, M.L., Rodríguez-Romero, A., Bustos-Jaimes, I.* (2023). Substrate binding in the allosteric site mimics homotropic cooperativity in the SIS-fold Glucosamine-6-phosphate deaminases. Protein Sci. 32(6), e4651. IF=8.0

- Trapala, J., González-Andrade, M., Olvera, C., Cayetano-Cruz, M., Sanz-Aparicio, J., Jimenez-Ortega, E., Bustos-Jaimes, I., Montiel, C. (2023). Relevance of aromatic and polar amino acids in the specificity of Inulinase ISO3 from Kluyveromyces marxianus: A molecular dynamics approach with an experimental verification. Int. J. Biol. Macromol. 242 (2023), 124734. IF=8.2

- Gutiérrez-Antón, M., Santiago-Hernández, A., Rodríguez-Mendoza, J., Cano-Ramírez, C., Bustos-Jaimes, I., Aguilar-Osorio, G., Campos, J.E., Hidalgo-Lara, M.E. (2023). Improvement of Laccase production by Thielavia terrestris Co3Bag1. Enhancing the bio-catalytic performance of the native thermophilic TtLacA via immobilization in copper alginate gel beads. J. Fungi, 9(3), 308. IF=4.7

- López-López, A., Santiago-Hernández, A., Cayetano-Cruz, M.E. Campos, J.E., Bustos-Jaimes, I., Marsch-Moreno, R., Cano-Ramírez, C., Benítez-Cardoza, C.G., Hidalgo-Lara, M.E. (2023). TtCel7A: A native thermophilic bifunctional cellulose/xylanase exogluclanase from the thermophilic biomass-degrading fungus Thielavia terrestris Co3Bag1, and its application in enzymatic hydrolysis of agroindustrial derivatives. J. Fungi, 9(2), 152. IF=4.7

- Münch-Anguiano, L., Camarena, B., Nieto-Quinto, J., de la Tore, P., Laclette, J.P., Hirata-Hernández, H., Hernández-Muñoz, S., Aguilar-García, A., Becerra-Palars, C., Gutiérrez-Mora, D., Ortega-Ruiz, H., Escamilla-Orozco, R., Saracco-Álvarez R., Bustos-Jaimes, I. (2022). Genetic analysis of the ZNF804A gene in Mexican patients with schizophrenia, schizoaffective disorder and bipolar disorder. Gene 829, 146508. IF=3.913

- Soto-Valerio, I.A., Cayetano-Cruz, M., Valadez-García, J., Guadarrama, P., Méndez, C., Bustos-Jaimes, I.* (2022). In vitro refolding of the structural protein VP1 of parvovirus B19 produces virus-like particles with functional VP1 unique region. Virology 570, 57-66. IF=3.7

- Barreda-Huerta, F., Bustos-Jaimes, I., Mújica-Jiménez, C., Muñoz-Clares, R.A. (2021). Multiple conformations in solution of the maize C4-phosphoenolpyruvate carboxylase isozyme. Heliyon 7, e08464. IF=4.0

- Jiménez-Chávez, A.J., Nava-García, B.K., Bustos-Jaimes, I., Moreno-Fierros, L. (2021). B19-VLPs as an effective delivery system for tumour antigens to induce humoral and cellular immune responses against triple negative breast cancer. Immunol. Lett. 239, 77-87. IF=4.4

- Trapala, J., Bustos-Jaimes, I., Manzanares, P., Bárzana, E., Montiel, C. (2020). Purification and characterization of an inulinase produced by a Kluyveromyces marxianus strain isolated from Blue Agave Bagasse. Protein Expr. Purif. 176, 105718. IF=1.6

- Terrazas-López, M., Lobo-Galo, N., Aguirre-Reyes, L.G., Bustos-Jaimes, I., Marcos-Víquez, J.A., González-Segura, L., Díaz-Sánchez, A.G. (2020). Interaction of N-succinyl diaminopimelate desuccinylase with orphenadrine and disulfiram. J. Mol. Struct. 1222, 128928. IF=3.8

- Jiménez-Chávez, A.J., Moreno-Fierros, L., Bustos-Jaimes, I. (2019). Therapy with multi-epitope virus-like particles of B19 parvovirus reduce tumor growth and lung metastasis in an aggressive breast cancer mouse model. Vaccine. 37 (49), 7256-7268. IF=5.5

- Cayetano-Cruz, M.E., Valadez-García, J., Mendez, C., Bustos-Jaimes, I.* (2019). Virus-like nanoparticles derived from parvovirus B19 efficiently internalize in human hepatocytes: A biocompatible delivery system for peptides and proteins. ACS Appl. Nano Mater. 2 (10), 6178-6186. IF=5.9

- Salazar-González, J.A., Ruiz-Cruz, A.A., Bustos-Jaimes, I., Moreno-Fierros, L. (2019). Expression of breast cancer-related epitopes targeting the IGF-1 receptor in chimeric human parvovirus B19 virus-like particles. Mol. Biotechnol. 61 (10), 742-753. IF=2.6

- Martínez-González, A.I., Díaz-Sánchez, A.G., De La Rosa, L.A., Bustos-Jaimes, I., Alvarez-Parrilla, E. (2019). Inhibition of a-amylase by flavonoids: Structure activity relationship (SAR). Spectrochim. Acta A: Mol. Biomol. Spectrosc. 206, 437-447. IF=4.4

- Aguirre-Díaz, I., Montiel, C., Bustos-Jaimes, I., Medina-Gonzalez, Y., Tecante, A., Gimeno, M. (2018). Chemoenzymatic synthesis of polypeptides in neat 1,1,1,2-tetrafluoroethane solvent. RSC Adv. 8, 35936-35945. IF=3.9

- Cayetano-Cruz, M., Coffeen, C.F., Valadez-García, J., Montiel, C., Bustos-Jaimes, I.* (2018). Decoration of virus-like particles with an enzymatic activity of biomedical interest. Virus Res. 255, 1-9. IF=5.0

- Espadín, A., Tamay De Dios, L., Ruvalcaba, E., Valadez-García, J., Velasquillo, C., Bustos-Jaimes, I., Vázquez-Torres, H., Gimeno, M., Shirai, K. (2018). Production and characterization of a nanocomposite of highly crystalline nanowhiskers from biologically extracted chitin in enzymatic Poly(-caprolactone). Carbohydr. Polym. 181, 684-692. IF=11.2
Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx
UNAM Posgrado