Contacto
Campos de conocimiento
Biofísica
Bioquímica
Fisiología Molecular
Líneas de investigación
Biofísica molecular de canales iónicos de potasio sensibles al voltaje. Espectroscopía y métodos ópticos aplicados al estudio de canales iónicos. Biología molecular de canales iónicos
Publicaciones
1. Voltage-dependent gating and gating charge measurements in the Kv1.2 potassium channel Itzel G. Ishida, Gisela E. Rangel-Yescas, Julia Carrasco-Zanini, and León D. Islas J Gen Physiol. 2015 En prensa. (*)(FI 4.57)
2. A simple method for fast temperature changes and its application to thermal activation of TRPV1 ion channels. Islas LD, De-la-Rosa V, Rodríguez-Cortés B, Rangel-Yescas GE, Elias-Viñas D. J Neurosci Methods. 2015 Feb 11. pii: S0165-0270(15)00053-9. doi: 10.1016/j.jneumeth.2015.02.003. (*)(FI 1.959)
3. Membrane pacman: small steps for the voltage-sensitive phosphatases.
Islas LD. J Physiol. 2014 Mar 1;592(Pt 5):823-4.(*) (FI 4.54)
4. Coarse architecture of the transient receptor potential vanilloid 1 (TRPV1) ion channel determined by fluorescence resonance energy transfer. De-la-Rosa V, Rangel-Yescas GE, Ladrón-de-Guevara E, Rosenbaum T, Islas LD. J Biol Chem. 2013 Oct 11;288(41):29506-17. (*)(FI 4.6)
5. Effects of electrical polarization on the opening rate constant of a voltage-gated ion channel. Ramírez-SanJuan GR, Minzoni AA, Islas LD. Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Jul;88(1):012720. Epub 2013 Jul 17(*)(FI 2.326)
6. The assembly and distribution in vivo of the Escherichia coli RNA degradosome.
Domínguez-Malfavón L, Islas LD, Luisi BF, García-Villegas R, García-Mena J.
Biochimie. 2013 Nov;95(11):2034-41. (FI 3.12)
7. The role of allosteric coupling on thermal activation of thermo-TRP channels.
Jara-Oseguera A, Islas LD. Biophys J. 2013 May 21;104(10):2160-9. (*)(FI 3.832)
8. Recovery from slow inactivation of Shab K(+) channels. Arias-Olguín II, Carrillo E, Islas LD, Gómez-Lagunas F. Channels (Austin). 2013 May-Jun;7(3):225-8. (FI 2.317)
9. The electric heart of hERG. Islas LD. J Gen Physiol. 2013 Apr;141(4):409-11. (*) (FI 4.57)
10. Shab K (+) channel slow inactivation: a test for U-type inactivation and a hypothesis regarding K (+) -facilitated inactivation mechanisms. Carrillo E, Arias-Olguín II, Islas LD, Gómez-Lagunas F. Channels (Austin). 2013 Mar-Apr;7(2):97-108. (FI 2.317)
11. Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site.
Nieto-Posadas A, Picazo-Juárez G, Llorente I, Jara-Oseguera A, Morales-Lázaro S, Escalante-Alcalde D, Islas LD, Rosenbaum T. Nat Chem Biol. 2011 Nov 20;8(1):78-85. doi: 10.1038/nchembio.712. (*)(FI 13.217)
12. Identification of a binding motif in the S5 helix that confers cholesterol sensitivity to the TRPV1 ion channel. Picazo-Juárez G, Romero-Suárez S, Nieto-Posadas A, Llorente I, Jara-Oseguera A, Briggs M, McIntosh TJ, Simon SA, Ladrón-de-Guevara E, Islas LD, Rosenbaum T. J Biol Chem. 2011 Jul 15;286(28):24966-76. (FI 4.6)
13. Uncoupling charge movement from channel opening in voltage-gated potassium channels by ruthenium complexes. Jara-Oseguera A, Ishida IG, Rangel-Yescas GE, Espinosa-Jalapa N, Pérez-Guzmán JA, Elías-Viñas D, Le Lagadec R, Rosenbaum T, Islas LD. J Biol Chem. 2011 May 6;286(18):16414-25. (*)(FI 4.6)
