Acceso a usuarios
Bienvenid@

Tutores

BALTAZAR BECERRIL LUJAN

Instituto de Biotecnología (IBT)

Contacto

Teléfono: 55 56 22 7669
Email: baltazar@ibt.unam.mx
Sitio web: Visitar sitio web

Campos de conocimiento

Biotecnología
Reconocimiento Molecular y Bioestructura

Líneas de investigación

Anticuerpos Recombinantes como Antivenenos.

Publicaciones

65.- Rodriguez-Rodriguez,E.R. Ledezma-Candanoza,L.M. Contreras-Ferrat,L.G. Olamendi-Portugal,T. Possani,L.D. Becerril,B. Riano-Umbarila,L. 2012. A Single Mutation in Framework 2 of the Heavy Variable Domain Improves the Properties of a Diabody and a Related Single-Chain Antibody. J.Mol.Biol., 423, 337-350.

66.- Aguilar,M.B. Ortiz,E. Kaas,Q. Lopez-Vera,E. Becerril,B. Possani,L.D. de la Cotera,E.P. 2013. Precursor De13.1 from Conus delessertii defines the novel G gene superfamily. Peptides, 41, 17-20.

67.- Riaño-Umbarila, L., Timoteo Olamendi-Portugal, Citlalli Morelos-Juárez,
Georgina B. Gurrola, Lourival D. Possani and Baltazar Becerril. 2013. A novel human recombinant antibody fragment capable of neutralizing Mexican scorpion toxins. Toxicon, 76, 370-376.

68.- González-Andrade, M., Baltazar Becerril-Luján., Sánchez-López, R.,
Ceceña-Alvarez, H., Pérez-Carreó, J.I., Ortiz-Suri, E., Alejandro D. Fernández-Velasco, A.D. and Luis del Pozo-Yauner. 2013. Mutational and genetic determinants of λ6 light chain amyloidogenesis. The FEBS Journal, 280, 6173-6183.

69.- Villalba,M.I., Canul-Tec,J.C., Luna-Martinez,O.D., Sanchez-Alcala,R., Olamendi-Portugal,T., Rudino-Pinera,E., Rojas,S., Sanchez-Lopez,R., Fernandez-Velasco,D.A., Becerril,B. 2015. Site-directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human lambda3r Light Chains J Biol Chem, 290, 2577-2592.

70.- Quintero-Hernandez,V. Ramirez-Carreto,S. Romero-Gutierrez,M.T. Valdez-Velazquez,L.L. Becerril,B. Possani,L.D. Ortiz,E. 2015.Transcriptome Analysis of Scorpion Species Belonging to the Vaejovis Genus PLoS ONE, 10, e0117188.

71.- Zuñiga-Navarrete, Fernando; Gómez, Isabel; Peña, Guadalupe; Amaro, Itzel; Ortiz Suri, Ernesto; Becerril, Baltazar; Ibarra, Jorge; Bravo de la Parra, Maria Alejandra; Soberón Chávez, Mario. 2015. Identification of Bacillus thuringiensis Cry3Aa toxin Domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12. Insect Biochemistry and Molecular Biology, 59, 50-57.

72.- Ramirez-Carreto,S., Jimenez-Vargas,J.M., Rivas-Santiago, B., Corzo, G., Possani, L.D., Becerril,B., Ortiz, E. 2015. Peptides from the scorpion Vaejovis punctatus with broad antimicrobial activity Peptides, 73, 51-59.

73.- Riano-Umbarilla, L., Ledezma-Candanoza, L.M., Serrano-Posada, H., Fernandez-Taboada, G. Olamendi-Portugal,T. Rojas-Trejo,S. Gomez-Ramirez,I.V. Rudino-Pinera,E. Possani,L.D. Becerril,B. 2016. Optimal neutralization of Centruroides noxius venom is understood through a structural complex between two antibody fragments and the Cn2 toxin Journal of Biological Chemistry, 291, 1619-1630.

74.- Olamendi-Portugal,T., Bartok,A. Zamudio-Zuniga,F. Balajthy,A. Becerril,B. Panyi,G. Possani,L.D. 2016. Isolation, chemical and functional characterization of several new K-channel blocking peptides from the venom of the scorpion Centruroides tecomanus Toxicon, 115, 1-12.

75.- Oscar D., Luna-Martínez , Abraham Vidal-Limón , Miryam I. Villalba-Velázquez , Rosalba Sánchez-Alcalá , Ramón Garduño-Juárez , Vladimir N. Uversky and Baltazar Becerril. 2016. Simple approach for ranking structure determining residues. PeerJ, Vol.E2136, Pag.1-23.

76.- Everardo Remi Rodríguez-Rodríguez, Timoteo Olamendi-Portugal, Hugo Serrano-Posada, Jonathan Noé Arredondo-López, Ilse Gómez-Ramírez, Guillermo Fernández-Taboada, Lourival D. Possani, Gerardo Alfonso Anguiano-Vega, Lidia Riaño-Umbarila., Baltazar Becerril. 2016. Broadening the neutralizing capacity of a family of antibody fragments against different toxins from Mexican scorpions. Toxicon, 119, 52-63.

77.- Olamendi-Portugal, T., Restano-Cassulini,R. Riano-Umbarila,L. Becerril,B. Possani,L.D. 2017. Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion Centruroides limpidus. Peptides, 87, 34-40.

78. - Riano-Umbarila, L. Rodriguez-Rodriguez, E.R. Santibanez-Lopez, C.E. Guereca, L. Uribe-Romero, S.J. Gomez-Ramirez, I.V. Carcamo-Noriega, E.N. Possani, L.D. Becerril, B. 2017. Updating knowledge on new medically important scorpion species in Mexico. Toxicon, 138, 130-137.

79. Luna-Martínez, O. D., Hernández-Santoyo, A., Villalba-Velázquez, M. I., Sánchez-Alcalá, R., Fernández-Velasco, D. A. and Becerril, B. (2017), Stabilizing an amyloidogenic λ6 light chain variable domain. FEBS J, 284: 3702–3717.

80. Edson Norberto Carcamo-Noriegaa , Timoteo Olamendi-Portugala , Rita Restano-Cassulinia , Ashlee Roweb , Selene Jocelyn Uribe-Romeroa , Baltazar Becerrila , Lourival Domingos Possani (2018) Intraspecific variation of Centruroides sculpturatus scorpion venom from two regions of Arizona. Archives of Biochemistry and Biophysiscs, 638: 52-57.


81. Delgado-Prudencio,G. Possani,L.D. Becerril,B. Ortiz,E. 2019. The Dual alpha-Amidation System in Scorpion Venom Glands Toxins (Basel), 11, 425.

82. Ruiz-Zamora,R.A. Guillaume,S. Al-Hilaly,Y.K. Al-Garawi,Z. Rodriguez-Alvarez,F.J. Zavala-Padilla,G. Perez-Carreon,J.I. Rodriguez-Ambriz,S.L. Herrera,G.A. Becerril-Lujan,B. Ochoa-Leyva,A. Melendez-Zajgla,J. Serpell,L. Del Pozo-Yauner,L. 2019. The CDR1 and Other Regions of Immunoglobulin Light Chains are Hot Spots for Amyloid Aggregation Scientific Reports, 9, 3123.

83. Riano-Umbarila,L. Gomez-Ramirez,I.V. Ledezma-Candanoza,L.M. Olamendi-Portugal,T. Rodriguez-Rodriguez,E.R. Fernandez-Taboada,G. Possani,L.D. Becerril,B. 2019. Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms Toxins (Basel), 11, 32.

84. Riano-Umbarila,L. Rojas-Trejo,V.M. Romero-Moreno,J.A. Costas,M. Utrera-Espindola,I. Olamendi-Portugal,T. Possani,L.D. Becerril,B. 2020. Comparative assessment of the VH-VL and VL-VH orientations of single-chain variable fragments of scorpion toxin-neutralizing antibodies Molecular Immunology, 122, 141-147.

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx
UNAM Posgrado