Contacto
Campos de conocimiento
Biofísica
Farmacología
Fisiología Molecular
Reconocimiento Molecular y Bioestructura
Líneas de investigación
Fisiología y Farmacología molecular de canales de calcio tipo T.
Canalopatías de canales de calcio tipo T.
Participación de los canales de sodio activados por voltaje en la metástasis del cáncer.
Publicaciones
1. Sánchez-Sandoval AL, Herrera-Carrillo Z, Díaz-Velásquez CE, Delgadillo DM, Rivera MH & Gomora JC. 2018. Contribution of S4 segments and S4-S5 linkers to the low-voltage activation properties of T-type CaV3.3 channels. PLoS One 13(2): e0193490. https://doi.org/10.1371/journal.pone.0193490.
2. Lopez-Charcas O, Espinosa AM, Alfaro A, Herrera-Carrillo Z, Ramirez-Cordero BE, Cortes-Reynosa P, Berumen J, Perez Salazar E & Gomora JC. 2018. The invasiveness of human cervical cancer associated to Nav1.6 channel activity is mediated by MMP2 activity. Sci Rep 8(1):12995. https://doi.org/10.1038/s41598-018-31364-y.
3. Arteaga-Tlecuitl R, Sanchez-Sandoval AL, Ramirez-Cordero BE, Rosendo-Pineda MJ, Vaca L & Gomora JC. 2018. Increase of Cav3 channel activity induced by HVA β1b-subunit is not mediated by a physical interaction. BMC Res Notes 11:810. https://doi.org/10.1186/s13104-018-3917-1.
4. Sanchez-Sandoval AL & Gomora JC. 2019. Contribution of voltage-gated sodium channel β-subunits to cervical cancer cells metastatic behavior. Cancer Cell Int 19:35. https://doi.org/10.1186/s12935-019-0757-6.
5. De La Rosa JAM, García-Castañeda M, Nishigaki T, Gomora JC, Mancilla-Percino T & Ávila G. 2020. Interaction of MDIMP with the voltage-gated calcium channels. Mol Pharmacol 98:211-221. https://doi.org/10.1124/mol.120.119982.
6 Lopez-Charcas O, Pukkanasut P, Velu, SE, Brackenbury WJ, Hales TG, Besson P, Gomora JC & Roger S. 2021. Pharmacological and nutritional targeting voltage-gated sodium channels in the treatment of cancers. iScience 24, 102270. https://doi.org/10.1016/j.isci.2021.102270.
7. Ruelas-Callejas A, Aguilar MB, Arteaga-Tlecuitl R, Gomora JC, López-Vera E. 2022. The T-1 conotoxin μ-SrVA from the worm hunting marine snail Conus spurius preferentially blocks the human NaV1.5 channel. Peptides. 156:170859. https://doi.org/10.1016/j.peptides.2022.170859.
