Acceso a usuarios
Bienvenid@

Tutores

ROBERTO ARREGUIN ESPINOSA

Instituto de Química (IQ)

Contacto

Teléfono: 55 56224770 Ext. 46617
Email: arrespin@gmail.com
Sitio web: Visitar sitio web

Campos de conocimiento

Bioquímica
Biotecnología
Farmacología
Reconocimiento Molecular y Bioestructura

Líneas de investigación

La Investigación que se realiza en el Laboratorio se enfoca a toxinas de organismos venenosos que son una fuente farmacológica de péptidos. A pesar de la gran cantidad y variedad de toxinas que estos organismos pueden producir. Utilizamos técnicas espectroscópicas como Dicroísmo Circular, Resonancia Magnética Nuclear, Espectroscopia Diferencial en el ultravioleta y Espectrometría de Masas de Alta Resolución.

Publicaciones

80) Recombinant O-mannosylated protein production (PstS-1) from Mycobacterium tuberculosis in Pichia pastoris (Komagataella phaffii) as a tool to study tuberculosis infection. Giroshi Bando-Campos, Daniel Juárez López, Sergio A Román-González, Antonia Castillo-Rodal, Clarita Olvera, Yolanda López Vidal, Roberto Arreguín-Espinosa, Mauricio A. Trujillo-Roldán and Norma A. Valdez-Cruz. Microbial Cell Factories. 18(11): 2019. https://doi.org/10.1186/s12934-019-1059-3 F.I. 3.831. ISSN: 1475-2859

81) A novel phospholipase A2 isolated from Palythoa caribaeorum possesses neurotoxic activity. Miguel Cuevas Cruz; Fernando Lazcano-Pérez, Ulises Hernández-Guzmán, K. Helena Díaz de la Vega-Castañeda, Sergio A. Román-González, Norma A. Valdez-Cruz, Ana Laura Colín-González, Abel Santamaría, Benjamín Velasco-Bejarano, Saúl Gómez-Manzo, and Dr.; Roberto Arreguín-Espinosa*. Toxins, 11(89): 2019. doi: 103390/toxins11020089. F.I. 3.273. ISSN: 2072-6651

82) Rat aorta relaxation induced by the venom of Poecilotheria regalis involves the activation of the NO/cGMP pathway Luis Fernando Díaz-Peña, Raymundo Ramírez, Luis Cuéllar-Balleza, Manuel B. Aguilar, Fernando Lazcano-Pérez, Roberto Arreguín-Espinosa, César Ibarra-Alvarado, Alejandro García-Arredondo TOXICON 2019. doi: https://doi.org/10.1016/j.toxicon.03.010 F.I. 2.352. Print ISSN: 0041-0101 Online ISSN: 1879-3150 Link ISSN: 0041-0101

83) Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels. Jin Al-hua, Cristofori-Armstrong B., Rash Lanchain D., Roman-Gonzalez Sergio A., Arreguín-Espinosa R., Lewis Richard J., Alewood Paul F., Vetter Irina., Biochemical Pharmacology 164, 342-348, 2019. https://doi.org/10.1016/j.bcp.2019.04.025 F.I. 4.825 . ISSN: 0006-2952.

84) Crystal growth in gels from the mechanisms of crystal growth to control of polymorphism: New trends on theoretical and experimental aspects. Omar Velásquez-González, Camila Campos-Escamilla, Andrea Flores-Ibarra, Nuria Esturau-Escofet, Roberto Arreguín-Espinosa, Vivian Stojanoff, Mayra Cuéllar-Cruz, Abel Moreno. Crystals 9, 443, 2019. doi:10.3390/cryst9090443. F.I. 2.404. ISSN 2073-4352

85) Genetic variability and population structure of Mexican chickpea (Cicer arietinum L.) germplasm accessions revealed by microsatellite markers. Ernestina Valadez-Moctezuma, Anselmo de Jesús Cabrera-Hidalgo and Roberto Arreguín-Espinosa*. Journal of Plant Biochemistry and Biotechnology, 2019 https://doi.org/10.1007/s13562-019-00532-0 F.I. 1.038. ISSN: 0971-7811 Print 0974-1275 Online

86) Molecular Cloning and Exploration of the Biochemical and Functional Analysis of Recombinant Glucose-6-Phosphate Dehydrogenase from Gluconoacetobacter diazotrophicus PAL5. Edson Jiovany Ramírez-Nava, Daniel Ortega-Cuellar, Abigail González-Valdez, Rosa Angélica Castillo-Rodríguez, Gabriel Yaxal Ponce-Soto, Beatriz Hernández-Ochoa, Noemí Cárdenas-Rodríguez, Víctor Martínez-Rosas, Laura Morales-Luna, Hugo Serrano-Posada, Edgar Sierra-Palacios, Roberto Arreguin-Espinosa, Miguel Cuevas-Cruz, Luz María Rocha-Ramírez, Verónica Pérez de la Cruz, Jaime Marcial-Quino and Saúl Gómez-Manzo International Journal of Molecular Science 20, 5279, 2019, doi:10.3390/ijms20215279 F.I. 3.687. ISSN 1422-0067

87) Quantification and stereochemical composition of R-(-) and S-(+)-clenbuterol enantiomers in Bovine urine by Liquid Chromatography-Tandem Mass Spectrometry. Benjamín Velasco-Bejarano, Jahir Bautista, Martha E. Rodríguez, Raquel López-Arellano, Roberto Arreguín-Espinosa and Ricardo Velasco Carrillo. Journal of Analytical Toxicology. 43 (9):1-8, 2019. doi:10.1093/jat/bkz087 F.I. 3.150. ISSN: 0146-4760

88) Formation of crystalline silica-carbonate biomorphs of alkaline earth metals (Ca, Ba, Sr) from ambient to low temperatures: Chemical implications during the primitive Earth´s life. Moreno, Abel; Cuéllar-Cruz, Mayra; Schneider, Dieter; Stojanoff, Vivian; Islas, Selene; Sánchez-Puig, Nuria; Arreguin-Espinosa, Roberto; Delgado, José Miguel. Crystal Growth & Design, 2020. doi:10.1021/acs.cgd.9b01473 F.I. 4.153 ISSN: 1528-7483

89) Identification of the NADP+ structural binding site and coenzyme effect on the fused G6PD::6PGL protein from Giardia lamblia. Laura Morales-Luna , Abigail González-Valdez, Yudibeth Sixto-López, José Correa-Basurto, Beatriz Hernández-Ochoa, Noemí Cárdenas-Rodríguez, Rosa Angélica Castillo-Rodríguez, Daniel Ortega-Cuellar, Roberto Arreguin-Espinosa, Verónica Pérez de la Cruz, Hugo Serrano-Posada, Sara Centeno-Leija, Luz María Rocha-Ramírez, Edgar, Sierra-Palacios, Alba Mónica Montiel-González, Yadira Rufino-González, Jaime Marcial-Quino, Saúl Gómez-Manzo. Biomolecules, 10 (1): 46, 2020. doi:10.3390/biom10010046 F.I. 4.694 ISSN: 2218-273X

90) Overexpression of the triosephosphate isomerase gene and effect on the metabolism of the protozoan Giardia lamblia. Jaime Marcial-Quino *, Saúl Gómez-Manzo*, Yadira Rufino-González, Beatriz Henández-Ocho, Daniel Ortega-Cuellar, Berenice, Franco-Juárez, Abigail González-Valdez, Fabiola Santos, Verónica Pérez de la Cruz, Roberto Arreguin-Espinosa, Luz María Rocha-Ramírez, Rosa Angélica Castillo-Rodríguez, Edgar Sierra-Palacios, Horacio Reyes-Vivas. Microorganisms, 8 (1): 40, 2020. doi:10.3390/microorganisms8010040 F.I. 4.167 ISSN 2076-2607

91) Gene Cloning, Recombinant Expression, Characterization, and Molecular Modeling of the Glycolytic Enzyme Triosephosphate Isomerase from Fusarium oxysporum. Beatriz Hernández-Ochoa Saúl Gómez-Manzo Erick Alcaraz-Carmona ,Hugo Serrano-Posada , Sara Centeno-Leija, Roberto Arreguin-Espinosa, Miguel Cuevas-Cruz, Abigail González-Valdez, José Alberto Mendoza-Espinoza, Marcelo Acosta Ramos, Leyda Cortés-Maldonado, Alba Mónica Montiel-González, Verónica Pérez de la Cruz, Luz María Rocha-Ramírez, Jaime Marcial-Quino, and Edgar Sierra-Palacios. Microorganisms, 8, (40), 2020. doi:10.3390/microorganisms8010040, 2020 F.I. 4.167 ISSN 2076-2607

92) Effects of Single and Double Mutants in Human Glucose-6-Phosphate Dehydrogenase Variants Present in the Mexican Population: Biochemical and Structural Analysis. Víctor Martínez-Rosas, Merit Valeria Juárez-Cruz, Edson Jiovany Ramírez-Nava, Beatriz Hernández-Ochoa, Laura Morales-Luna, Abigail González-Valdez, Hugo Serrano-Posada, Noemí Cárdenas-Rodríguez, Paulina Ortiz-Ramírez, Sara Centeno-Leija, Roberto Arreguin-Espinosa, Miguel Cuevas-Cruz, Daniel Ortega-Cuellar, Verónica Pérez de la Cruz, Luz María Rocha-Ramírez, Edgar Sierra-Palacios, Rosa Angélica Castillo-Rodríguez, Isabel Baeza-Ramírez, Jaime Marcial-Quino and Saúl Gómez-Manzo. Int. J. Mol. Sci., 21, 2732, 2020. F.I. 4.556 doi:10.3390/ijms21082732. ISSN 1422-0067

93) Identification of α-Glucosidase Inhibitors from Ipomoea alba by Affinity-Directed Fractionation-Mass Spectrometry. Rosas-Ramírez, D., Pereda-Miranda, R., Escandón-Rivera, S. and Arreguín-Espinosa, R* Rev. Bras. Farmacogn. 2020. https://doi.org/10.1007/s43450-020-00068-8 ISSN: 0102-695X

94) Characterizing the fused TvG6PD::6PGL Protein from The Protozoan Trichomonas vaginalis, effects of the NADP Molecule on Enzyme Stability. Laura Morales-Luna, Beatriz Hernández-Ochoa, Edson Ramírez-Nava, Víctor Martínez-Rosas, Paulina Ortiz-Ramírez, Fernández-Rosario, Abigail González-Valdez, Noemí Cárdenas-Rodríguez Hugo Serrano-Posada, Sara Centeno-Leija, Roberto Arreguin-Espinosa, Miguel Cuevas-Cruz, Daniel Ortega-Cuellar, Verónica Pérez de la Cruz, Luz María Rocha-Ramírez, Edgar Sierra-Palacios, Rosa Angélica Castillo-Rodríguez Vanesa Vega-García, Yadira Rufino-González, Jaime Marcial-Quino and Saúl Gómez-Manzo. Int. J. Mol. Sci. 2020, F.I. 4.556 21 (14),4831, Special Issue Computational Studies of Biomacromolecules doi.org/10.3390/ijms21144831. ISSN 1422-0067

95) Functional and structural analysis and molecular modeling of the Glucose-6-phosphate dehydrogenase-Phosphogluconolactonase protein from protozoan Trichomonas vaginalis. Laura Morales-Luna, Beatriz Hernández-Ochoa, Edson Ramírez-Nava, Víctor Martínez-Rosas, Paulina Ortiz-Ramírez, Fernández-Rosario, Abigail González-Valdez, Noemí Cárdenas-Rodríguez Hugo Serrano-Posada, Sara Centeno-Leija, Roberto Arreguin-Espinosa, Miguel Cuevas-Cruz, Daniel Ortega-Cuellar, Verónica Pérez de la Cruz, Luz María Rocha-Ramírez, Edgar Sierra-Palacios, Rosa Angélica Castillo-Rodríguez Vanesa Vega-García, Yadira Rufino-González, Jaime Marcial-Quino and Saúl Gómez-Manzo. Int. J. Mol. Sci. 2020, F.I. 4.556 21 (14),4831, Special Issue Computational Studies of Biomacromolecules doi.org/10.3390/ijms21144831. ISSN 1422-0067

96) Enhanced Antigiardial Effect of Omeprazole Analog Benzimidazole Compounds. Beatriz Hernández-Ochoa, Saúl Gómez-Manzo, Adrián Sánchez-Carrillo, Jaime Marcial-Quino, Luz María Rocha-Ramírez, Araceli Santos-Segura, Edson Jiovany Ramírez-Nava, Roberto Arreguin-Espinosa, Miguel Cuevas-Cruz, Alfonso Méndez-Tenorio and Ernesto Calderón-Jaimes. Molecules 2020, F.I. 3.267 25, 3979; doi: https://doi.org/10.3390/molecules25173979

97) Glucose 6-phosphatase and alpha-glucosidase inhibitors from Smilax moranensis roots identified by affinity-directed fractionation. Rosas-Ramírez, D., Pereda-Miranda, R., Escandón-Rivera, S. and Arreguín-Espinosa, R* Rev. Bras. Farmacogn. https://doi.org/10.1007/s43450-020-00116-3, 2021. ISSN: 0102-695X

98) Novel inhibitors of human glucose-6-phosphate dehydrogenase (HsG6PD) affect the activity and stability of the protein. Edson Jiovany Ramírez-Nava, Beatriz Hernández-Ochoa, Gabriel Navarrete-Vázquez, Roberto Arreguín-Espinosa, Daniel Ortega-Cuellar, Abigail González-Valdez, Víctor Martínez-Rosas, Laura Morales-Luna, Josué Martínez-Miranda, Edgar Sierra-Palacios, Luz María Rocha-Ramírez, Lucia De Franceschi, Jaime Marcial-Quino and Saúl Gómez-Manzo. BBA General Subjects. 2021. DOI:10.1016/j.bbagen.2020.129828, F.I. 3.422. ISSN 0304-4165

99) The influence of silicateins on the shape and crystalline habit of silica carbonate biomorphs of alkaline earth metals (Ca, Ba, Sr). Nuria Sánchez-Puig*, Mayra Cuéllar-Cruz, Selene R. Islas, V. Tapia-Vieyra, Roberto A. Arreguín-Espinosa, Abel Moreno. Submitted to Crystals, 11 (4), 438, 2021. https://doi.org/10.3390/cryst. F.I. 2404. 11040438 ISSN 2073-4352.

100) Glucose-6-Phosphate Dehydrogenase::6-Phosphogluconolactonase from the parasite Giardia lamblia. A molecular and Biochemical Perspective of a Fused Enzyme. Morales-Luna. L., González-Valdez, A.,Hernández-Ochoa, B., Arrequín-Espinosa, R., Ortega-Cuellar, D., Castillo-Rodríguez, R. A., Martínez-Rosas, V., Cárdenas-Rodríguez, N., Enríquez-Flores, S., Canseco-Avila, L. M., Pérez de la Cruz, V., Gómez-Chávez, F. and Gómez-Manzo, S. Microorganisms 9, 1678, 2021. http//doi.org/10.3390/microorganisms9081678 F.I. 4.167 ISSN 2076-2607

101) Effects of High Dietary Carbohydrate and Lipid Intake on the Lifespan of C. elegans. Franco-Juárez B., Gómez-Manzo, S., Hernández-Ochoa, B., Cárdenas-Rodríguez, N., Arreguín-Espinosa, R., Pérez de la Cruz, V. and Ortega-Cuellar, D. Cells 10, 2359, 2021. https://doi.org/10.3390/cells10092359 F.I. 7.666 ISSN 2073-4409.

102) Kinetic and molecular docking studies to determine the effect of inhibitors on the activity and structure of fused G6PD::6PGL protein from Trichomonas vaginalis. Víctor Martínez-Rosas, Beatriz Hernández-Ochoa, Gabriel Navarrete-Vázquez, Carlos Martínez-Conde, Fernando Gómez-Chávez, Laura Morales-Luna, Abigail González-Valdez, Roberto Arreguin-Espinosa, Sergio, Enríquez-Flores, Verónica Pérez de la Cruz, Rodrigo Aguayo-Ortiz, Carlos, Wong-Baeza, Isabel Baeza-Ramírez, Saúl Gómez-Manzo. Molecules 25, 3979, 2022 F.I. 3.267 https://doi.org/10.3390/molecules27041174 F.I. 4.412 ISSN 14203049.

103) Chemical structure of three basic Asp-49 phospholipases A2 isolated from Crotalus molossus nigrescens venom with cytotoxic activity against cancer cells. Fernando Lazcano-Pérez, Edgar Rangel, Benjamín Robles-Bañuelos, Adrián Marcelo Franco-Vásquez, Alejandro García-Arredondo, Ariana Zavala-Moreno, Juan Carlos Navarro-García, Saul Gómez-Manzo and Roberto Arreguín-Espinosa*. Toxicon, Vol 210, 25-31, 2022. F.I. 3.033. ISSN: 2590-1710. https://doi.org/10.1016/j.toxicon.2022.02.013

104) A sea anemone Lebrunia neglecta venom fraction decreases boar sperm cells capacitation: possible involvement of HVA calcium channels. Fernando Lazcano-Pérez, Karina Bermeo, Héctor Castro, Zayil Salazar Campos, Isabel Arenas, Ariana Zavala-Moreno, Sheila Narayán Chávez-Villela, Irma Jiménez, Roberto Arreguín-Espinosa, Reyna Fierro Humberto González-Márquez, David E. García, and Judith Sánchez-Rodríguez. Toxicon, Vol 220, 25-31, 2022. https://doi.org/10.3390/toxins14040261 F.I. 3.033. ISSN: 2590-1710.

105) The role of mass spectrometry in the Discovery of antibiotics and bacterial resistance mechanism: proteomics and metabolomics approaches. Miguel Cuevas-Cruz, Ulises Hernández-Guzmán, Poulette Álvarez-Rosales, Meike Schnabel, Saúl Gómez-Manzo and Roberto Arreguín-Espinosa*. Current Medicinal Chemistry Vol 29 (42) 2022. F.I. 4.53. ISSN :1875-533X. doi:10.2174/0929867329666220329090822.

106) Chemical characterization of fruits of yellow-orange and purple varieties of Opuntia ficus-indica and thermal stability of their betalains. Juan Pablo Carreón, Angelica Roman, Arturo Navarro-Ocana, Darío R. Gómez-Linton, Diana Carolina Franco-Vásquez, Adrián Marcelo Franco-Vásquez, Roberto Arreguín-Espinosa, Laura J. Pérez-Flores. Journal of Food Science

107) Biochemical and Kinetic Characterization of the Glucose-6-phosphate dehydrogenase from Helicobacter pylori Strain 29CaP. Paulina Ortiz-Ramírez, Beatriz Hernández-Ochoa, Daniel Ortega-Cuellar, Abigail González-Valdez, Víctor Martínez-Rosas, Laura Morales-Luna, Roberto Arreguin-Espinosa, Rosa Angélica Castillo-Rodríguez, Luis Miguel Canseco-Ávila, Noemi Cárdenas-Rodríguez, Verónica Pérez de la Cruz, Alba Mónica Montiel-González, Fernando Gómez-Chávez, Saúl Gómez-Manzo. Microorganisms 9 , 1678, 2022. https://doi.org/10.3390/microorganisms10071359 F.I. 4.167 ISSN 2076-2607.

108) COVID-19 Times: Impact on Information Generation and Data Sharing. Eden Rodriguez-Flores, Saul Gomez-Manzo, Jaime Marcial-Quino, Roberto Arreguín-Espinosa, Eduardo Rodríguez-Bustamante. Advances in Internet of Things 12, 65-87, 2022. F.I. 1.85. DOI:10.4236/ait.2022.123005 ISSN: 2161-6825.

109) TFEB, beyond its role as an autophagy and lysosomes regulator. Berenice Franco-Juárez, Cristina Coronel-Cruz, Beatriz Hernández-Ochoa, Saúl Gómez-Manzo, Noemi Cárdenas-Rodríguez, Roberto Arreguin-Espinosa, Cindy Bandala, Luis Miguel Canseco-Ávila, Daniel Ortega-Cuellar*. Cells 11(19), 3153. https://doi.org/10.3390/cells11193153 F.I. 7.666 ISSN 2073-4409

110) Giardia lamblia G6PD ::6PGL fused protein inhibitors decrease trophozoite viability: a new alternative against giardiasis. Laura Morales-Luna, Beatriz Hernández-Ochoa, Víctor Martínez-Rosas, Gabriel Navarrete-Vázquez, Daniel Ortega-Cuellar, Yadira Rufino-González, Abigail González-Valdez, Roberto Arreguin-Espinosa, Adrián Marcelo Franco-Vásquez, Verónica Pérez de la Cruz, Sergio Enríquez-Flores, Carlos Martínez-Conde, Luis Miguel Canseco-Ávila,Fernando Gómez-Chávez, Saúl Gómez-Manzo*. Int. J. Mol. Sci. 2022, DOI:10.3390/biom10010046 F.I. 4.556. ISSN 1422-0067

111) Phytochemical screening and new Ent-clerodane diterpenoids from Croton guatemalensis Lotsy. Sonia Marlen Escandón-Rivera, Adolfo Andrade-Cetto *, Daniel Genaro Rosas-Ramírez, Roberto Arreguín-Espinosa. Plants. 2022. F.I. 4.827. ISSN 2223-7747

112) Nitro-group-containing pyridyl methylsulfinyl benzimidazole derivatives as promising agents against Giardia lamblia and Trichomonas vaginalis. Beatriz Hernández Ochoa, Víctor Martínez Rosas, Laura Morales Luna, Ernesto Calderon Jaimes, Luz María Rocha Ramírez, Daniel Ortega Cuellar, Yadira Rufino González, Abigail González Valdez, Roberto Arrreguin Espinosa, Sergio Enríquez Flores, Rosa Angélica Castillo Rodríguez, Noemí Cárdenas Rodríguez, Carlos Wong Baeza, Isabel Baeza Ramírez, Saul Gómez Manzo*. Pharmaceuticals F.I. 5.215. ISSN 1424-8247

113) Identification of Holothurin A from body wall of sea cucumber Holothuria inornata by ultra-performance liquid chromatography-tandem mass spectrometry (GNPL-2017-2441) has been submitted by E. López-Sampedro, J. Calderón, M. Honey-Escandón, R. Arreguín-Espinosa*, and F. A. Solís-Marín. Submitted to Biochemical Biophysical Research Communications, F.I. 2.559. ISSN: 0006-291X

114) Conventional and non-conventional extraction of functional compounds from jiotilla (Escontria chiotilla) fruits and evaluation of their antioxidant activity D.C. Franco-Vásquez, J.P. Carreón-Hidalgo, D.R. Gómez-Linton, A. Román-Guerrero, A.M. Franco-Vásquez, R. Arreguín-Espinosa, S. Alavez, L.J. Pérez-Flores. Revista Mexicana de Ingeniería Química. 2023, Vol 22, N°7, Alim2963. DOI: 10.24275/rmiq/Alim2963

115) Methylsulfinyl Benzimidazole Derivatives as Promising Agents against Giardia lamblia and Trichomonas vaginalis. Hernández-Ochoa, B.; Martínez-Rosas, V.; Morales-Luna, L.; Calderón-Jaimes, E.; Rocha-Ramírez, L.M.; Ortega-Cuellar, D.; Rufino-González, Y.; González-Valdez, A.; Arreguin-Espinosa, R.; Enríquez-Flores, S.; Castillo-Rodríguez, R.A.; Cárdenas-Rodríguez, N.; Wong-Baeza, C.; Baeza-Ramírez, I.; Gómez-Manzo, S. Pyridyl. Molecules 2022, 27, 8902. DOI: 10.3390/molecules27248902

116) Díaz-Peña, L. F., Daniela, T. O., Aguilar, M. B., Luis, E., Lazcano-Pérez, F., Arreguín-Espinosa, R., Hernandez-Cruz, A., Ibarra-Alvarado, C., & García-Arredondo, A. (2023). A subfraction obtained from the venom of the tarantula Poecilotheria regalis contains inhibitor cystine knot peptides and induces relaxation of rat aorta by inhibiting L-type voltage-gated calcium channels. Toxicon: X, 18, 100151. DOI: 10.1016/j.toxcx.2023.100151

117) Motolinia-Alcántara, E. A., Franco-Vásquez, A. M., Nieto-Camacho, A., Arreguín-Espinosa, R., Rodríguez-Monroy, M., Cruz-Sosa, F., & Román-Guerrero, A. (2023). Phenolic Compounds from Wild Plant and In Vitro Cultures of Ageratina pichichensis and Evaluation of Their Antioxidant Activity. Plants, 12(5), 1107. DOI: 10.3390/plants12051107

118) DNAddicts: Learning genetic engineering with a worker placement board game. Eden Rodriguez-Flores, Saul Gomez Manzo, Patricia Vázquez-Villegas, Jorge Membrillo-Hernández, Roberto Arreguín-Espinosa, Eduardo Rodríguez-Bustamante. Biochemistry and Molecular Biology Education BAMBED, 2023. F.I. 1.369 ISSN: 1539-3429 DOI: 10.1002/bmb.21778

119) Nitazoxanide inhibits the bifunctional enzyme GlG6PD::6PGL of Giardia lamblia: biochemical and in silico characterization of a new druggable target. Víctor Martínez-Rosas, Beatriz Hernández-Ochoa, LauraMorales-Luna, Daniel Ortega-Cuellar, Abigail González-Valdez, Roberto Arreguin-Espinosa, Yadira Rufino-González, Ernesto Calderón-Jaimes, RosaAngélica Castillo-Rodríguez, Carlos Wong-Baeza, Isabel Baeza-Ramírez, Verónica Pérez de la Cruz, Abraham Vidal-Limón*, Saúl Gómez-Manzo*. Int. J. Mol. Sci. 2023, 24 (14) DOI: 10.3390/ijms241411516 F.I. 5.600. ISSN 1422-0067

120) An overall view of the functional and structural characterization of Glucose-6-phosphate dehydrogenase variants in the Mexican population. Beatriz Hernández-Ochoa, Daniel Ortega-Cuellar, Abigail González-Valdez, Víctor Martínez-Rosas, Laura Morales-Luna, Miriam Abigail Rojas-Acosta, Montserrat Vázquez-Bautista, Roberto Arreguin-Espinosa, Verónica Pérez de la Cruz, Rosa Angélica Castillo-Rodríguez, Luis MiguelCanseco-Ávila, Abraham Vidal-Limón, Saul Gómez-Manzo. Int. J. Mol. Sci. 2023, 24 (3) DOI: 10.3390/ijms241612691 F.I. 5.600. ISSN 1422-0067

121) A short and practical overview on Light-Sensing proteins, optogenetics, and fluorescent biomolecules inside biomorphs used as optical sensors. Galindo-García, U., Vanegas-Reza, M., Arreguín-Espinosa, R., Pérez, K. S., Pérez-Solis, R., Mendoza, M., Cervantes-Quintero, K. Y., Islas, S. R., Cuéllar‐Cruz, M., & Moreno, A. Crystals, 2023, 13(9), 1343. DOI: 10.3390/cryst13091343

122) Unveiling the venom composition of the Colombian coral snakes Micrurus helleri, M. medemi, and M. sangilensis. Ariadna Rodríguez-Vargas *, Adrián Marcelo Franco-Vásquez, Janeth Alejandra Bolívar-Barbosa, Nohora Vega, Edgar Reyes-Montaño, Roberto Arreguín-Espinosa, Alejandro Carbajal- Saucedo, Teddy Angarita-Sierra, Francisco Ruiz-Gómez. Toxins, Vol (): , 2023. DOI: 10.3390/toxins15110622 F.I. 4.2 ISSN: 2590-1710.

123) New alternatives in the fight against tuberculosis: Possible targets for resistant mycobacteria. Rodríguez-Bustamante, E., Gómez-Manzo, S., De Obeso Fernandez Del Valle, A., Arreguín-Espinosa, R., Espitia-Pinzón, C., & Rodríguez-Flores, E. Processes, 2023, 11(9), 2793. DOI: 10.3390/pr11092793

124) Structural, biochemical and immunochemical characterization of an acidic phospholipase A2 from Lachesis acrochorda (Viperidae: Crotalinae) venom. Franco‐Vásquez, A. M., Lazcano-Pérez, F., Mejía-Sánchez, M. A., Corzo, G., Zamudio, F., Carbajal-Saucedo, A., Román-González, S. A., Gómez-Manzo, S., & Arreguín‐Espinosa, R. Toxicon, 2023, 107528. DOI: 10.1016/j.toxicon.2023.107528

125) Fused Enzyme Glucose-6-Phosphate Dehydrogenase::6-Phosphogluconolactonase (G6PD::6PGL) as a Potential Drug Target in Giardia lamblia, Trichomonas vaginalis, and Plasmodium falciparum. Morales-Luna, L.; Vázquez-Bautista, M.; Martínez-Rosas, V.; Rojas-Alarcón, M.A.; Ortega-Cuellar, D.; González-Valdez, A.; Pérez de la Cruz, V.; Arreguin-Espinosa, R.; Rodríguez-Bustamante, E.; Rodríguez-Flores, E.; et al. Microorganisms 2024, 12, 112. https://doi.org/10.3390/microorganisms12010112

126) Immunological Cross-Reactivity and Preclinical Assessment of a Colombian Anticoral Antivenom against the Venoms of Three Micrurus Species. Rodríguez-Vargas, A.; Franco-Vásquez, A.M.; Triana-Cerón, M.; Alam-Rojas, S.N.; Escobar-Wilches, D.C.; Corzo, G.; Lazcano-Pérez, F.; Arreguín-Espinosa, R.; Ruiz-Gómez, F. Toxins 2024, 16, 104. https://doi.org/10.3390/toxins16020104

127) Identification of Hypoglycemic Glycolipids from Ipomoea murucoides by Affinity-Directed Fractionation, In Vitro, In Silico and Dynamic Light Scattering Analysis. Rosas-Ramírez, D.; Arreguín-Espinosa, R.; Escandón-Rivera, S.; Andrade-Cetto, A.; Mata-Torres, G.; Pérez-Solís, R. Plants 2024, 13, 644. https://doi.org/10.3390/plants13050644
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