Contacto
Campos de conocimiento
Bioquímica
Biotecnología
Fisiología Molecular
Microbiología Molecular
Líneas de investigación
Estudio de la regulación de los factores de virulencia por los sistemas sensores de quórum y el sistema Rsm en diferentes aislados de Pseudomonas aeruginosa.
Estudio de la producción de piocianina, su regulación génica por el sistema Rsm
Estudio de la respuesta autoprotectora ante la sobreproducción de piocianina en Pseudomonas aeruginosa.
Sobreproducción de fenazinas de interés médico e industrial utilizando a Pseudomonas aeruginosa ID4365
Publicaciones
1. Soto-Aceves, MP., Cocotl-Yañez, M., Merino, E., Castillo-Júarez, I., Cortés-López, H., González-Pedrajo, B., Díaz-Guerrero, M., Servín-González, L., Soberón-Chávez, G. Inactivation of the quorum-sensing transcriptional regulators LasR or RhlR does not supress the expression of virulence factors of Pseudomonas aeruginosa PAO1. Microbiology doi: 10.1099/mic.0.000778. (FI: 2.18)
2. Selene Reyes-García, Gloria Soberón-Chávez and Miguel Cocotl-Yañez*. 2020. The third quorum-sensing system of Pseudomonas aeruginosa: Pseudomonas Quinolone Signal and the enigmatic PqsE protein. Journal of Medical Microbiology. DOI 10.1099/jmm.0.001116 (FI: 2.15)
3. Cocotl-Yañez M*, Soto-Aceves MP, González-Valdez A, Servín-González L, Soberón-Chávez G. 2020. Virulence factors regulation by the quorum-sensing and Rsm Systems in the marine strain Pseudomonas aeruginosa ID4365, a natural mutant in lasR. FEMS Microbiology Letters. Jun 1;367(12):fnaa092 (FI: 1.98)
4. García-Reyes S, Soto-Aceves MP, Cocotl-Yañez M*, González-Valdez A, Servín-González L, Soberón-Chávez G. 2020. The outlier Pseudomonas aeruginosa strain ATCC 9027 harbors a detective LasR quorum-sensing transcriptional regulator. FEMS Microbiology Letters. Aug 1;367(16):fnaa122 (FI: 1.98)
5. Martínez-Ortíz I, Ahumada-Manuel C, Hsueh B, Guzman J, Moreno, S, Cocotl-Yañez M*, Water C, Zamorano-Sánchez D, Espin G, Nuñez C. 2020. Cyclic-di-GMP-mediated regulation of extracellular mannuronan C-5 epimerases is essential for cyst formation in Azotobacter vinelandii’. J Bact. Nov 19; 202(24):e00135-20 (FI: 3.21)
6. Soto-Aceves MP, Cocotl-Yañez M*, Servín-González L, Soberón-Chávez G. 2021. The Rhl quorum-sensing system is at the top of the regulatory hierarchy under phosphate-limiting conditions in Pseudomonas aeruginosa PAO1. J Bact. Feb 8;203 (5):e00475-20. (FI: 3.21)
7. Soberón-Chávez G, Soto-Aceves MP, González-Valdez A, Cocotl-Yañez M*. 2021. Rhamnolipids produced by Pseudomonas: from molecular genetics to the market. Microb Biotechnol. Jan;14(1): 136-146 (FI: 5.32)
8. Garcia-Reyes S, Cocotl-Yañez M, Soto-Aceves MP, González-Valdez A, Servín L, Soberón-Chávez G. 2021. The PqsR-independent quorum-sensing response of Pseudomonas aeruginosa ATCC 9027 outlier-strain reveals new insights on the PqsE effect on RhlR. Mol Microbiol. Oct;116(4):1113-1123. (FI: 3.5)
9. Montelongo-Martínez LF, Hernández-Méndez C, Muriel-Millan LF, Hernández-Estrada R, Fabian-Del Olmo MJ, González-Valdez A, Soberón-Chávez G, Cocotl-Yañez M. 2022. Unraveling the regulación of pyocyanin synthesis by RsmA through MvaU and RpoS in Pseudomonas aeruginosa ID4365. J Basic Microbiol. 2022;1–13. ) (FI-2.65)
10. Soto-Aceves MP, González-Váldez A, Cocotl-Yanez M, Soberón-Chávez G. 2022. Pseudomonas aeruginosa LasR overexpression leads to a ReaL-independent pyocyanin production inhibition in a low phosphate condition. Microbiology. Oct;168(10). doi: 10.1099/mic.0.001262. (FI: 2.8)
11. Muriel-Millán LF, Montelongo-Martínez LF, González-Valdez A, Bedoya-Perez LP, Cocotl-Yañez M, Soberón-Chávez G. The alternative sigma factor RpoS regúlales Pseudomonas aeruginosa quorum sensing response by repressing the pqsABCDE operon and activating vfr. Mol Microbiol. 2024 Feb;121(2):291-303 (FI:3.6)
