Contacto
Campos de conocimiento
Biofísica
Líneas de investigación
Homeostasis y dinámica del calcio intracelular en neuronas y células endocrinas.
Fisiología de las glándulas adenohipofisiaria y adrenal in vitro.
Regulación por GABA de la actividad de la celulas cromafines in vitro
Papel las célula cromafín adrenal en la fisiopatología de la hipertensión.
Canalopatias que afectan la funcion cardiaca y nerviosa
Reprogramacion de celulas pluripotentes humanas
Publicaciones
Forero-Vivas M E. and Hernández-Cruz, A. (2014). Increased firing frequency of spontaneous action potentials in cerebellar Purkinje neurons of db/db mice result from altered auto-rhythmicity and diminished GABAergic tonic inhibition. General Physiology and Biophysics 33:29-41. doi; 10.4149/gpb_2013056.
Darszon A and Hernández-Cruz A. (2014). T-type Ca2+ channels in spermatogenic cells and sperm. Pflugers Archives-European Journal of Physiology 466:819-883. doi: 10.1007/s00424-014-1478-1472
Sánchez-Cárdenas C, Servín-Vences MR, José O, Trevino CL, Hernández- Cruz A, and Darszon A. (2014). Acrosome Reaction and Ca2+ Imaging in Single Human Spermatozoa: New Regulatory Roles of [Ca2+]i Biology of Reproduction 91(3)67: 1-13. DOI 10.1095/biolreprod.114.119768
López-Bistrain P., Segura-Chama P. Jiménez-Pérez N. Rivera-Cerecedo
C.V. Hernández-Cruz A. (2014). The role of Ca2+ release from the endoplasmic reticulum in the catecholamine hypersecretion of adrenal chromaffin cells from spontaneously hypertensive rats. In Catecholamine Research in the 21st Century: Pages 53-54. Lee Eiden (Ed). Oxford, Elsevier.
Albiñana E, Segura-Chama P, Baraibar AM, Hernández-Cruz A. and Hernández-Guijo JM. (2015). Different contribution of calcium channel subtypes to electrical excitability of chromaffin cells in rat adrenal slices. Journal of Neurochemistry. 133(4): 511-521. doi: 10.1111/jnc.13055
Segura-Chama P., López-Bistrain P., Pérez-Armendáriz EM, Jiménez-Pérez N., Millán-Aldaco D. and Hernández-Cruz A. (2015). Enhanced Ca2+ induced Ca2+ release from intracellular stores contributes to catecholamine hypersecretion in adrenal chromaffin cells from spontaneously hypertensive rats. Pflugers Archives-European Journal of Physiology. 467(11): 2307-2323. doi 10.1007/s00424-015- 1702-8
Alejandre-García T., Segura-Chama P., Pérez-Armendáriz E.M., Delgado- Lezama, R., and Hernández-Cruz A (2016). Modulation of spontaneous intracellular Ca2+ fluctuations and spontaneous cholinergic transmission in rat chromaffin cells in situ by endogenous GABA acting on GABAA receptors. Pflugers Archives-European Journal of Physiology. 468:351-365. DOI 10.1007/s00424-015-1744-y
Romarowski A, Sánchez-Cárdenas C, Ramírez-Gómez HV, Puga Molina L, Treviño CL., Hernández-Cruz A, Darszon A, and Buffone MG. (2016). A Specific Transitory Increase in Intracellular Calcium Induced by Progesterone Promotes Acrosomal Exocytosis in Mouse Sperm. Biology of Reproduction 94(3):63, 1-12. Epub 2016 Jan 27. doi: 10.1095/biolreprod.115.136085,
Pérez-Ortega J, Duhne M, Lara-González E, Plata V, Gasca D, Galarraga E, Hernández-Cruz A, Bargas J. (2016). Pathophysiological signatures of functional connectomics in parkinsonian and dyskinetic striatal microcircuits. Neurobiology of Disease. 91:347-361. doi: 10.1016/j.nbd.2016.02.023.
Alvarez-Arce A, Lee-Rivera I, López E, Hernández-Cruz A and López-Colomé AM. (2017). Thrombin-induced Calpain Activation Promotes Protease-Activated Receptor 1 (PAR1) Internalization. International Journal of Cell Biology. Volume 2017, Article ID 1908310, 14 pages. https://doi.org/10.1155/2017/1908310. Aceptado oct 14 2017.
Barriga-Montoya C, de la O-Martínez A, Picones A, Hernández-Cruz A, Beatriz Fuentes-Pardo B, Gómez-Lagunas F. (2017). On desensitization and recovery of crayfish photoreceptors that follows the delivery of a light stimulus. JoVE (Journal of Visualized Experiments). Aceptado Noviembre 20, 2017.
Barriga-Montoya C, Huanosta-Gutiérrez A, Reyes Vaca A, Hernández-Cruz A, Picones-Medina A, Gómez-Lagunas F. (2017) Inhibition of the K+-conductance and Cole-Moore shift of the oncogenic Kv10.1 channel by amiodarone (2017). Pflugers Archives-European Journal of Physiology. Dec 7. doi: 10.1007/s00424-017-2092-x. [Epub ahead of print] PMID: 29218452 DOI: 10.1007/s00424-017-2092-x
Alejandre-García T, Peña-del Castillo JG and Hernández-Cruz A. (2018) GABAA receptor: a unique modulator of excitability, Ca2+ signaling, and catecholamine release of rat chromaffin cells. Pflugers Archives-European Journal of Physiology Jan;470(1):67-doi: 10.1007/s00424-017-2080-1. Epub 2017 Nov 3. Review. PMID: 29101464.
Sánchez-Cárdenas C, Montoya F, Navarrete FA, Hernández-Cruz A, Corkidi G, Visconti PE, Darszon A (2018). Intracellular Ca2+ threshold reversibly switches flagellar beat off and on. Biology of Reproduction, ioy132, https://doi.org/10.1093/biolre/ioy132 Pub 8 June 2018.
González-Suarez AM, Peña-Del Castillo JG, Hernández-Cruz A, Garcia-Cordero JL. (2018). Dynamic generation of concentration- and temporal-dependent chemical signals in an integrated microfluidic device for single-cell analysis. Analytical Chemistry. 90(14):8331-8336. doi: 10.1021/acs.analchem.8b02442. Epub 2018 Jul 5. PMID: 29916698.
