Mis líneas de investigación actuales son:
El estudio del metabolismo de RNA y la epitranscriptómica.
La genómica funcional de trastornos conductuales y neurodegenerativos.
El uso de las vesículas extracelulares como medio de drug delivery y diagnostico de mínima invación.

Publicaciones

Briones-Orta MA, Avendaño-Vázquez SE, Aparicio-Bautista DI, Coombes JD, Weber GF, Syn
WK, Osteopontin splice variants and polymorphisms in cancer progression and prognosis.
Biochim Biophys Acta. 2017 Feb 27. pii: S0304-419X(17)30006-9. doi:
10.1016/j.bbcan.2017.02.005. [Epub ahead of print] Review.

Briones-Orta MA, Avendaño-Vázquez SE, Aparicio-Bautista DI, Coombes JD, Weber GF, Syn
WK, Prediction of Transcription Factor Binding Sites affected by SNPs located at the
Osteopontin Promoter, Data in Brief, (Submitted for publication)

Bembich S, Herzog JS, De Conti L, Stuani C, Avendaño-Vázquez SE, Buratti E, Baralle M,
Baralle FE. Predominance of spliceosomal complex formation over polyadenylation site
selection in TDP-43 autoregulation. Nucleic Acids Res. 2014 March; 42(5): 3362-71. PMID:
24369426

Hernández-Méndez A, Alcántara-Hernández R, Acosta-Cervantes GC, Martínez-Ortiz J,
Avendaño-Vázquez SE, García-Sáinz JA. Conventional protein kinase C isoforms mediate
phorbol ester-induced lysophosphatidic acid LPA1 receptor phosphorylation. Eur J Pharmacol.
2014 Jan 15; 723: 124-130. PMID: 24355769

Avendaño-Vázquez SE, Dhir A, Bembich S, Buratti E, Proudfoot NJ, Baralle FE.
Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing and
alternative polyA site selection. Genes Dev. 2012 Aug 1; 26(15):1679-84. PMID: 22855830

Budini M, Romano V, Avendaño-Vázquez SE, Bembich S, Buratti E, Baralle FE. Role of
selected mutations in the Q/N rich region of TDP-43 in EGFP-12xQ/N-induced aggregate
formation. Brain Res. 2012 Jan 26;1462:139-50. PMID: 22406069

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx