1. Genómica, Epigenómica y Farmacogenómica de la leucemia aguda linfoblástica infantil: búsqueda de biomarcadores de recaída y de nuevos blancos terapeúticos.

2. Mitogenómica y Oncogénesis en de la glándula mamaria: el papel de las mutaciones del genoma mitocondrial en el desarrollo del cáncer de mama y en la gravedad de la enfermedad.

Publicaciones

Mendoza Rincón JF, Rodríguez Elias AK, Fragoso JM, Vargas Alarcón G, Maldonado Murillo K, Rivas Jiménez ML, Barbosa Cobos RE, Jimenez Morales S, Lugo Zamudio G, Tovilla Zárate C, Ramírez Bello J. MHC2TA and FCRL3 genes are not associated with rheumatoid arthritis in Mexican patients. Rheumatol Int. 2016;36:249-54.
Mendoza Rincón JF, López Cano D, Jiménez Morales S, Rivas Jiménez ML, Barbosa Cobos RE, Ramírez Bello J. The functional PTPN22 C1858T polymorphism confers risk for rheumatoid arthritis in patients from Central Mexico. Clin Rheumatol. 2016;35:1457-62.
Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, et al [175 colaboradores]. Analysis of protein-coding genetic variation in 60,706 humans. Nature. 2016;536:285-91.
Mejía-Aranguré JM, Núñez-Enríquez JC, Fajardo-Gutiérrez A, Rodríguez-Zepeda MD, Martín-Trejo JA, Duarte-Rodríguez DA, Medina-Sansón A, Flores-Lujano J, Jiménez- Hernández E, Núñez-Villegas NN, Pérez-Saldívar ML, Paredes-Aguilera R, Cárdenas- Cardós R, Flores-Chapa JD, Reyes-Zepeda NC, Flores-Villegas LV, Amador-Sánchez R, Torres-Nava JR, Bolea-Murga V, Espinosa-Elizondo RM, Peñaloza-González JG, Velázquez-Aviña MM, González-Bonilla C, Békker-Méndez VC, Jiménez-Morales S, Martínez-Morales GB, Vargas HR, Rangel-López A. [Descriptive epidemiology of children with acute myeloid leukemia residing in Mexico City: a report from the Mexican Inter- Institutional Group for Identifying Childhood Leukemia Causes]. Gac Med Mex. 2016 Oct; 152(Suppl
Jimenez-Morales S*, Ramírez-Florencio M, Núñez-Enríquez JC. et al . Analysis of the thiopurine S-methyltransferase mutant alleles in Mexican children with acute lymphoblastic leukemia. Arch Med Research. Arch Med Res. 2016;47(8):615-622.
Núñez-Enríquez JC, Bárcenas-López DA, Hidalgo-Miranda A, Jiménez-Hernándezc E; Bekker-Méndez VC, Flores-Lujanoa J, Solis-Labastida K, Martínez-Moralesa G, Sánchez-Muñoz G, Espinoza-Hernández L, Velázquez-Aviña M, Merino-Pasayeh L, García-Velázquez A, Pérez-Saldívara MA, Mojica-Espinoza R, Ramírez-Bello J, Jiménez-Morales S*, Juan Manuel Mejía-Aranguré JM, MIGICC. Arch Med Res. 2016;47(8):644-655.
Jiménez-Morales S*, Hidalgo-Miranda A, Ramírez-Bello J. Leucemia linfoblástica aguda infantil: una aproximación genómica. [Acute lymphoblastic leukemia: a genomic perspective]. Bol Med Hosp Infant Mex. 2017;74(1):13-26.
Alemán-Ávila I, Jiménez-Morales M, Beltrán-Ramírez O. Barbosa-Cobos RE, Jiménez- Morales S, Sánchez-Muñoz F, Valencia-Pacheco G, Amezcua-Guerra LM, Juárez- Vicuña Y, Razo-Blanco Hernández DM, Aguilera Cartas MC, López Villanueva R, Peralta Zaragoza O, Tovilla Zárate C, Ramírez Bello Julian. Functional polymorphisms in pre-miR146a and pre-miR499 are associated with systemic lupus erythematosus but not with rheumatoid arthritis or Graves' disease in Mexican patients. Oncotarget 2017; 8(54): 91876-91886.
Mendieta-Zeron H, Jiménez-Rosales A, Pérez-Amado CJ, Jiménez-Morales S. FOXE1 mutation screening in a case with Cleft lip, hypothyroidism and thyroid carcinoma: A new syndrome?. Case Rep Genet. 2017;2017:6390545.
Ramirez-Florencio M, Jiménez-Morales S*, Cobos Barbosa RE, López-Cano DJ, Ramírez-Bello J. High frequency of mutant thiopurine s-methyltransferase genotypes in Mexican patients with systemic lupus erythematous and rheumatoid arthritis. Clin Rheumatol, 2018, 37(4), 963-970
Jiménez-Hernández E, Fajardo-Gutiérrez A, Núñez-Enriquez JC, Martín-Trejo JA, Espinoza-Hernández LE, Flores-Lujano J, Arellano-Galindo J, Medina-Sanson A, Paredes-Aguilera R, Merino-Pasaye LE, Velázquez-Aviña MM, Torres-Nava JR, Espinosa-Elizondo RM, Amador-Sánchez R, Dosta-Herrera JJ, Mondragón-García JA, Valdés-Guzmán H, Mejía-Pérez L, Espinoza-Anrubio G, Paz-Bribiesca MM, Salcedo- Lozada P, Landa-García RÁ, Ramírez-Colorado R, Hernández-Mora L, Pérez-Saldivar ML, Santamaría-Ascencio M, López-Loyola A, Godoy-Esquivel AH, García-López LR, Anguiano-Ávalos AI, Mora-Rico K, Castañeda-Echevarría A, Rodríguez-Jiménez R, Cibrian-Cruz JA, Solís-Labastida KA, Cárdenas-Cardos R, Martínez-Avalos A, Flores- Villegas LV, Peñaloza-González JG, González-Ávila AI, Altamirano-García MB, López- Santiago N, Sánchez-Ruiz M, Rivera-Luna R, Rodríguez-Villalobos LR, Hernández- Pérez F, Olvera-Durán JÁ, García-Cortés LR, Mata-Rocha M, Sepúlveda-Robles OA, González-Bonilla CR, Bekker-Méndez VC, Jiménez-Morales S, Rosas-Vargas H, Mejía- Aranguré JM. A greater birthweight increases the risk of acute leukemias in Mexican children-experience from the Mexican Interinstitutional Group for the Identification of the Causes of Childhood Leukemia (MIGICCL). Cancer Med. 2018; 7(4):1528-1536.
Ramírez-Bello J, Cadena-Sandoval D, Mendoza-Rincón JF, Barbosa-Cobos RE, Sánchez-Muñoz F, Amezcua-Guerra LM, Sierra-Martínez M, Jiménez-Morales S. Tumor necrosis factor gene polymorphisms are associated with systemic lupus erythematosus susceptibility or lupus nephritis in Mexican patients. Immunol Res.2018;66(3):348-354.
Ramírez-Bello J, Cadena-Sandoval D, Jiménez-Morales S, Fragoso JM, Barbosa- Cobos RE, Moreno Eutímio MA, Saavedra Salinas MA, Valencia-Pacheco G, López- Villanueva R. The VEGFA -1154G/A polymorphism is associated with reduced risk of rheumatoid arthritis but not with systemic lupus erythematosus in Mexican women. Journal of Gene Medicine. 20(6):e3024.
Jiménez-Morales S*, Pérez-Amado CJ, Langley E, Hidalgo-Miranda A. Overview of mitochondrial germline variants and mutations in human disease: focus on breast cancer. International Journal Oncology. 2018 Sep;53(3):923-936. FI. 3.899
Soto ME, Montufar-Robles I, Jiménez-Morales S, Gamboa R, Huesca-Gómez C, Ramírez-Bello J. An association study in PTPN22 suggests that is a risk factor to Takayasu's arteritis. Inflamm Res. 2019 68(3):195-201. FI. 3.174
Fernández-Lopez JC, Romero-Córdoba S, Rebollar-Vega R, Alfaro-Ruiz LA, Jiménez- Morales S, Beltrán-Anaya F, Arellano-Llamas R, Cedro-Tanda A, Rios-Romero M, Ramirez-Florencio M, Bautista-Piña V, Dominguez-Reyes C, Villegas-Carlos F, Tenorio- Torres A, Hidalgo-Miranda A. Population based analysis of genomic variation of the BRCA 1 genes in the Mexican Population. Hum Genomics. 2019;13(1):3. FI: 3.35
Beltrán-Anaya, F; Romero-Córdoba, S; Rebollar-Vega, R; Arrieta, O; Bautista-Piña, V; Domínguez-Reyes, C; Villegas-Carlos, F; Tenorio-Torres, A; Jiménez-Morales, S; Alfaro- Riuz, L; Cedro-Tanda, A; Ríos-Romero, M; Tagliabue, E; Iorio, M; Hidalgo-Miranda, A. Expression of Long non-coding RNA ENSG00000226738 (LncKLHDC7B) is enriched in the immunomodulatory triple negative breast cancer subtype and its alteration promotes cell migration, invasion and resistance to cell death. Mol Oncol. 2019;13(4):909-927. FI: 3.35
Cruz-Miranda GM, Hidalgo-Miranda A, Bárcenas-López DA, Mejía-Aranguré JM, Núñez- Enriquez JC, Ramírez-Bello J, Jiménez-Morales S*. Long non-coding RNA and acute leukemia. I Int J Mol Sci. 2019;20(3). FI: 4.556. FI: 2.83
Rodríguez-Cortés YM, Amaya-Chávez A, García-Fabila, Jiménez-Morales S, Pérez-Amado CJ, Mendieta-Zerón H. SHβX1 Splice Variant Expression and D2 Thr92Ala Polymorphism Analysis in Pregnant Women with Thyroid Diseases. SN Comprehensive Clinical Medicine. 2019.
Mata-Rocha M, Mejía-Arenguré JM, Rangel-López, A Jiménez-Hernández E, Morales- Castillo BA, González-Torres C, Gaytan-Cervantes J, Álvarez-Olmos E, Fajardo- Gutiérrez A, Martín-Trejo JA, Solís-Labastida KA, Medina-Sansón A, Flores-Lujano J, Peñaloza-González JG, Espinoza-Hernández LE, Núñez-Villegas NN, Espinosa- Elizondo RM, Cortés-Herrera B, Torres-Nava JR, Flores-Villegas LV, Merino-Pasaye LE, Bekker-Méndez VC, Velázquez-Aviña MM, Pérez-Saldívar ML, Bautista-Martínez BA, Amador-Sánchez R, González-Avila AI, Jiménez-Morales S, Rosas-Vargas H, Duarte- Rodríguez DA, Sepúlveda-Robles OA, Núñez-Enríquez JC, Santillán-Juárez JD, García- Velázquez AJ. Identification and Characterization of novel fusion genes with potential clinical applications in Mexican Children with acute lymphoblastic leukemia. Int J Mol Sci. 2019;20(10). FI: 4.55
Ramírez-Bello J, Jiménez-Morales S, Montufar-Robles I, Fragoso JM, Barbosa-Cobos RE, Saavedra MA, Sánchez-Muñoz F. BLK and BANK1 polymorphisms and interactions are associated in Mexican patients with systemic lupus erythematosus. Inflamm Res. 2019 Aug;68(8):705-713. FI. 3.174
Núñez-Enríquez JC, Gil-Hernández AE, Jiménez-Hernández E, Fajardo-Gutiérrez A, Medina-Sansón A, Flores-Lujano J, Espinoza-Hernández LE, Duarte-Rodríguez DA, Amador-Sánchez R, Peñaloza-González JG, Torres-Nava JR, Espinosa-Elizondo RM, Flores-Villegas LV, Merino-Pasaye LE, Pérez-Saldivar ML, Dorantes-Acosta EM, Cortés- Herrera B, Solis-Labastida KA, Núñez-Villegas NN, Velázquez-Aviña MM, Rangel-López A, González-Ávila AI, Santillán-Juárez JD, García-Velázquez AJ, Jiménez-Morales S, Bekker-Méndez VC, Rosas-Vargas H, Mata-Rocha M, Sepúlveda-Robles OA, Martín- Trejo JA, Mejía-Aranguré JM. Overweight and obesity as predictors of early mortality in Mexican children with acute lymphoblastic leukemia: a multicenter cohort study. BMC Cancer. 2019;19(1):708. FI: 3.0
De la Cruz-Cano E, Jiménez-González CDC, Morales-García V, Pineda-Pérez C, Tejas- Juárez JG, Rendón-Gandarilla FJ, Jiménez-Morales S, Díaz-Gandarilla JA. Arg913Gln variation of SLC12A3 gene is associated with diabetic nephropathy in type 2 diabetes and Gitelman syndrome: a systematic review. BMC Nephrol. 2019;20(1):393. FI: 2.0
González-Ramírez C, Villavicencio Queijeiro A, Jiménez Morales S, Bárcenas-López D, Hidalgo Miranda A, Ruiz-Chow A,-Tellez Cárdenas L, Guardado-Estrada M. The NR3C1 gene expression is a potential surrogate biomarker for risk and diagnosis of posttraumatic stress disorder. Psychiatry Res. 2020;284:112797.
Ramírez-Bello J, Fragoso JM, Alemán-Ávila I, Jiménez-Morales S, Campos-Parra AD, Barbosa-Cobos RE, Moreno J. Association of BLK and BANK1 Polymorphisms and Interactions With Rheumatoid Arthritis in a Latin-American Population. Front Genet. 2020;11:58. FI: 3.2
Bárcenas-López DA, Núñez-Enríquez JC, Hidalgo-Miranda A, Beltrán-Anaya FO, May- Hau DI, Jiménez-Hernández E, Bekker-Méndez VC, Flores-Lujano J, Medina-Sansón A, Tamez-Gómez EL, López-García VH, Lara-Ramos JR, Núñez-Villegas NN, Peñaloza- González JG, Flores-Villegas LV, Amador-Sánchez R, Espinosa-Elizondo RM, Martín- Trejo JA, Velázquez-Aviña MM, Merino-Pasaye LE, Pérez-Saldívar ML, Duarte- Rodríguez DA, Torres-Nava JR, Cortés-Herrera B, Solís-Labastida KA, González-Ávila AI, Santillán-Juárez JD, García-Velázquez AJ, Rosas-Vargas H, Mata-Rocha M, Sepúlveda-Robles OA, Mejía-Aranguré JM, Jiménez-Morales S. Transcriptome Analysis Identifies LINC00152 as a Biomarker of Early Relapse and Mortality in Acute Lymphoblastic Leukemia. Genes (Basel). 2020;11(3). FI: 3.759
Jiménez-Hernández E, Duarte-Rodríguez DA, Núñez-Enriquez JC, Flores-Lujano J, Martín-Trejo JA, Espinoza-Hernández LE, Arellano-Galindo J, Medina-Sanson A, García-Jiménez X, Paredes-Aguilera R, Flores-Villegas LV, Peñaloza-González JG, Torres-Nava JR, Espinosa-Elizondo RM, Amador-Sánchez R, Dosta-Herrera JJ, Mondragón-García JA, Valdés-Guzmán H, Mejía-Pérez L, Espinoza-Anrubio G, Paz-Bribiesca MM, Salcedo-Lozada P, Landa-García RÁ, Ramírez-Colorado R, Hernández-Mora L, Pérez-Saldivar ML, Santamaría-Ascencio M, López-Loyola A, Godoy-Esquivel AH, García-López LR, Anguiano-Ávalos AI, Mora-Rico K, Castañeda-Echevarría A, Rodríguez-Jiménez R, Cibrian-Cruz JA, Cárdenas-Cardos R, Altamirano-García MB, Sánchez-Ruiz M, Rivera-Luna R, Rodríguez-Villalobos LR, Hernández-Pérez F, Olvera-Durán JÁ, García-Cortés LR, Mata-Rocha M, Sepúlveda-Robles OA, Bekker-Méndez VC, Jiménez-Morales S, Rosas-Vargas H, Mejía-Aranguré JM Maternal and paternal ages at conception of index child and risk of childhood acute leukaemia: A multicentre case-control study in Greater Mexico City. Cancer Epidemiol. 2020;67:101731. FI: 2.17
Cedro-Tanda A, Ríos-Romero M, Romero-Córdoba S, Cisneros-Villanueva M, Rebollar-Vega RG, Alfaro-Ruiz LA, Jiménez-Morales S, Domínguez-Reyes C, Villegas-Carlos F, Tenorio-Torres A, Bautista-Piña V, Beltrán-Anaya FO, Hidalgo-Miranda A. A lncRNA landscape in breast cancer reveals a potential role for AC009283.1 in proliferation and apoptosis in HER2-enriched subtype. Sci Rep. 2020;10(1):13146. Published 2020 Aug 4. doi:10.1038/s41598-020-69905-z. FI: 3.998
Ríos-Romero M, Cedro-Tanda A, Peña-Luna M, Mancera-Rodríguez MA, Hidalgo-Pérez L, Cisneros-Villanueva M, Beltrán-Anaya FO, Arellano-Llamas R, Jiménez-Morales S, Alfaro-Ruíz LA, Tenorio-Torres A, Domínguez-Reyes C, Villegas-Carlos F, Ochoa-Mendoza E, Hidalgo-Miranda A. FAM83H-AS1 is a potential modulator of cancer driver genes across different tumors and a prognostic marker for ER/PR + BRCA patients. Sci Rep. 2020;10(1):14145. Published 2020 Aug 24. FI: 3.998
Aurora Medina-Sanson, Juan Carlos Núñez-Enríquez, Eduardo Hurtado-Córdova, María Luisa Pérez-Saldívar, Anayeli Martínez-García, JIMENEZ HERNANDEZ ELVA, Juan Carlos Fernández-López, Jorge Alfonso Martín-Trejo, Héctor Pérez-Lorenzana, Janet Flores-Lujano, Raquel Amador-Sánchez, Félix Gustavo Mora-Ríos, José Gabriel Peñaloza-González, David Aldebarán Duarte-Rodríguez, José Refugio Torres-Nava, Juan Eduardo Flores-Bautista, Rosa Martha Espinosa-Elizondo, Pedro Francisco Román-Zepeda, Luz Victoria Flores-Villegas, Juana Esther González-Ulivarri, Sofía Irene Martínez-Silva, Gilberto Espinoza-Anrubio, Carolina Almeida-Hernández, Rosario Ramírez-Colorado, Luis Hernández-Mora, Luis Ramiro García-López, Gabriela Adriana Cruz-Ojeda, Arturo Emilio Godoy-Esquivel, Iris Contreras-Hernández, Abraham Medina-Hernández, María Guadalupe López-Caballero, Norma Angélica Hernández-Pineda, Jorge Granados-Kraulles, María Adriana Rodríguez-Vázquez, Delfino Torres-Valle, Carlos Cortés-Reyes, Francisco Medrano-López, Jessica Arleet Pérez-Gómez, Annel Martínez-Ríos, Antonio Aguilar-De los Santos, Berenice Serafín-Díaz, Vilma Carolina Bekker-Mendez, Minerva Mata-Rocha, Blanca Angélica Morales-Castillo, Omar Alejandro Sepúlveda-Robles, Julian Ramírez-Bello, Haydeé Rosas-Vargas, Alfredo Hidalgo-Miranda, Juan Manuel Mejia Arangure, Silvia Jiménez-Morales. Frontiers in Ocology. Aceptado. FI 4.8

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx