Estudio de las vías de señalización involucradas en la activación del receptor a progesterona y/o estrógenos por proteínas cinasas C (PKCs) y su implicación en el desarrollo de tumores cerebrales.

Estudio de los cambios en la plasticidad neuronal en el transtorno autista.

Publicaciones

1. Barón-Mendoza I, Mejía-Hernández M, Hernández-Mercado K, Guzmán-Condado J, Zepeda A, González-Arenas A (autor correspondiente). Altered hippocampal neurogenesis in a mouse model of autism revealed by genetic polymorphisms and by atypical development of newborn neurons.
Sci Rep. 14(1):4608, 2024. FI: 4.6
2. Duarte-Campos JF, Vázquez-Moreno CN, Martínez-Marcial M, Chavarría A, Ramírez-Carreto RJ, Velasco Velázquez MA, De La Fuente-Granada M, González-Arenas A (autor correspondiente). Changes in neuroinflammatory markers and microglial density in the hippocampus and prefrontal cortex of the C58/J mouse model of autism. Eur J Neurosci. 59(1):154-173, 2024. FI: 3.4
3. Carlos-Escalante JA, Mejía-Pérez SI, Soto-Reyes E, Guerra-Calderas L, Cacho-Díaz B, Torres-Arciga K, Montalvo-Casimiro M, González-Barrios R, Reynoso-Noverón N, Ruiz-de la Cruz M, Díaz-Velásquez CE, Vidal-Millán S, Álvarez-Gómez RM, Sánchez-Correa TE, Pech-Cervantes CH, Soria-Lucio JA, Pérez-Castillo A, Salazar AM, Arriaga-Canon C, Vaca-Paniagua F, González-Arenas A, Ostrosky-Wegman P, Mohar-Betancourt A, Herrera LA, Corona T, Wegman-Ostrosky TDeep DNA sequencing of MGMT, TP53 and AGT in Mexican astrocytoma patients identifies an excess of genetic variants in women and a predictive biomarker. J Neurooncol.161(1):165-174, 2023. FI: 4.44
4. Hernández-Rojas R, Jiménez-Arellano C, de la Fuente-Granada M, Ordaz-Rosado D, García-Becerra R, Valencia-Mayoral P, de Lourdes Álvarez-Arellano M, Eguía-Aguilar P, Velasco-Velázquez MA, González-Arenas A (autor correspondiente). The interplay between estrogen receptor beta and protein kinase C, a crucial collaboration for medulloblastoma cell proliferation and invasion. Cell Signal.13:110246, 2022. FI: 4.8.
5. Barón-Mendoza I, Maqueda-Martínez E, Martínez-Marcial M, De la Fuente-Granada M, Gómez-Chavarin M, González-Arenas A (autor correspondiente). Changes in the Number and Morphology of Dendritic Spines in the Hippocampus and Prefrontal Cortex of the C58/J Mouse Model of Autism. Front Cell Neurosci. 15:726501, 2021. FI: 5.3
6. Arcos-Montoya D, Wegman-Ostrosky T, Mejía-Pérez S, De la Fuente-Granada M, Camacho-Arroyo I, García-Carrancá A, Velasco-Velázquez MA, Manjarrez-Marmolejo J, González-Arenas A (autor correspondiente). Progesterone Receptor Together with PKCα Expression as Prognostic Factors for Astrocytomas Malignancy. Onco Targets Ther. 16 (14) :3757-3768, 2021. FI: 4.0.
7. Valdés-Rives SA, Arcos-Montoya D, de la Fuente-Granada M, Zamora-Sánchez CJ, Arias-Romero LE, Villamar-Cruz O, Camacho-Arroyo I, Pérez-Tapia SM and González-Arenas A (autor correspondiente). LPA1 Receptor Promotes Progesterone Receptor Phosphorylation through PKC alpha in Human Glioblastoma Cells. Cells 10(4):807, 2021. FI:6.0.
8. Bello-Alvarez C, Moral-Morales AD, González-Arenas A, Camacho-Arroyo I. Intracellular Progesterone Receptor and cSrc Protein Working Together to Regulate the Activity of Proteins Involved in Migration and Invasion of Human Glioblastoma Cells. Front Endocrinol. 12:640298, 2021. FI: 5.2.
9. Hernández-Vega AM, Del Moral-Morales A, Zamora-Sánchez CJ, Piña-Medina AG, González-Arenas A, Camacho-Arroyo I. Estradiol Induces Epithelial to Mesenchymal Transition of Human Glioblastoma Cells. Cells. 9(9): E1930, 2020. FI:6.0.
10. Velázquez-Quesada I, Ruiz-Moreno AJ, Casique-Aguirre D, Aguirre-Alvarado C, Cortés-Mendoza F, de la Fuente-Granada M, García-Pérez C, Pérez-Tapia SM, González-Arenas A, Segura-Cabrera A, Velasco-Velázquez MA. Pranlukast Antagonizes CD49f and Reduces Stemness in Triple-Negative Breast Cancer Cells. Drug Des Devel Ther. 14:1799-1811, 2020. FI: 4.16.
11. Barón-Mendoza I, González-Arenas A (autor correspondiente). Relationship between the effect of polyunsaturated fatty acids (PUFAs) on brain plasticity and the improvement on cognition and behavior in individuals with autism spectrum disorder. Nutr Neurosci. April 25:1-24, 2020. FI: 3.6
12. González-Arenas A (corresponding author), De la Fuente-Granada M, Camacho-Arroyo I, Zamora-Sánchez CJ, Piña-Medina AG, Segura-Uribe J, Guerra-Araiza C. Tibolone Effects on Human Glioblastoma Cell Lines. Arch Med Res. 50:187-196. 2019. FI: 7.7
13. Vásquez-Bochm LX, Velázquez-Paniagua M, Castro-Vázquez SS, Guerrero-Rodríguez SL, Mondragon-Peralta A, De La Fuente-Granada M, Pérez-Tapia SM, González-Arenas A, Velasco-Velázquez MA. Transcriptome-based identification of lovastatin as a breast cancer stem cell-targeting drug. Pharmacol Rep. 71:535-544. 2019. FI: 4.4.
14. Barón-Mendoza I, Del Moral-Sánchez I, Martínez-Marcial M, García O, Garzón-Cortés D, González-Arenas A (autor correspondiente). Dendritic complexity in prefrontal cortex and hippocampus of the autistic-like mice C58/J. Neurosci Lett. 703:149-155. 2019. FI:2.5.
15. Valdés-Rives SA, de la Fuente-Granada M, Velasco-Velázquez MA, González-Flores O, González-Arenas A (autor correspondiente). LPA1 receptor activation induces PKCα nuclear translocation in glioblastoma cells. Int J Biochem Cell Biol. 110:91-102. 2019. FI: 4.0

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx