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Tutores

ERNESTO ORTIZ SURI

Instituto de Biotecnología (IBT)

Contacto

Teléfono: 777 3291669
Email: ernesto.ortiz@ibt.unam.mx
Sitio web: Visitar sitio web

Campos de conocimiento

Bioquímica

Líneas de investigación

Toxinología de venenos de alacranes y conos
Inmunología y estrategias de despliegue en fagos

Publicaciones

Delgado-Prudencio,G., Cid-Uribe,J.I., Morales,J.A., Possani,L.D., Ortiz,E., Romero-Gutierrez,T. (2022). The Enzymatic Core of Scorpion Venoms. Toxins, 14 (4), 248.

Okada,M., Ortiz,E. (2022). Therapeutic potential of viral vectors that express venom peptides for neurological diseases. Medical Hypotheses, 161, 110809.

Jimenez-Vargas,J.M., Ramirez-Carreto,S., Corzo,G., Possani,L.D., Becerril,B., Ortiz,E. (2021). Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus. Peptides, 141, 170553.

Santana,F.L., Estrada,K., Ortiz,E., Corzo,G. (2021). Reptilian beta-defensins: expanding the repertoire of known crocodylian peptides. Peptides, 136, 170473.

Cid-Uribe,J.I., Veytia-Bucheli,J.I., Romero-Gutierrez,T., Ortiz,E., Possani,L.D. (2020). Scorpion venomics: a 2019 overview. Expert Review of Proteomics, 17 (1), 67-83.

Bernaldez-Sarabia,J., Figueroa-Montiel,A., Duenas,S., Cervantes-Luevano,K., Beltran,J.A., Ortiz,E., Jimenez,S., Possani,L.D., Paniagua-Solis,J.F., Gonzalez-Canudas,J., Licea-Navarro,A. (2019). The Diversified O-Superfamily in Californiconus californicus Presents a Conotoxin with Antimycobacterial Activity. Toxins (Basel), 11 (2), E128.

Carcamo-Noriega,E.N., Possani,L.D., Ortiz,E. (2019). Venom content and toxicity regeneration after venom gland depletion by electrostimulation in the scorpion Centruroides limpidus. Toxicon, 157, 87-92.

Cid-Uribe,J.I., Meneses,E.P., Batista,C.V.F., Ortiz,E., Possani,L.D. (2019). Dissecting Toxicity: The Venom Gland Transcriptome and the Venom Proteome of the Highly Venomous Scorpion Centruroides limpidus (Karsch, 1879). Toxins (Basel), 11 (5), 247.

Delgado-Prudencio, G., Possani, L. D., Becerril, B., Ortiz, E. (2019). The Dual alpha-Amidation System in Scorpion Venom Glands. Toxins (Basel), 11 (7).

Okada,M., Ortiz,E., Corzo,G., Possani,L.D. (2019). Pore-forming spider venom peptides show cytotoxicity to hyperpolarized cancer cells expressing K+ channels: A lentiviral vector approach. PLoS ONE, 14 (4), e0215391.

Santibanez-Lopez,C.E., Graham,M.R., Sharma,P.P., Ortiz,E., Possani,L.D. (2019). Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures. Toxins (Basel), 11 (11), E637, E637.

Cid-Uribe, J.I., Santibanez-Lopez, C.E., Meneses, E.P., Batista, C.V.F., Jimenez-Vargas, J.M., Ortiz, E., Possani, L.D. (2018). The diversity of venom components of the scorpion species Paravaejovis schwenkmeyeri (Scorpiones: Vaejovidae) revealed by transcriptome and proteome analyses. Toxicon, 151, 47-62.

Ortiz, E., Possani, L.D. (2018). Scorpion toxins to unravel the conundrum of ion channel structure and functioning. Toxicon, 150, 17-27.

Romero-Gutierrez, M. T., Santibanez-Lopez, C. E., Jimenez-Vargas, J. M., Batista, C. V. F., Ortiz, E., Possani, L. D. (2018). Transcriptomic and Proteomic Analyses Reveal the Diversity of Venom Components from the Vaejovid Scorpion Serradigitus gertschi. Toxins (Basel), 10 (9), 359.

Garcia-Garcia, F., Corrales-Garcia, L.L., Olamendi-Portugal, T., Restano-Cassulini, R., Vega, R., Vega, M., Ortiz, E., Sandoval-Lopez, G., Soto, E., Corzo, G. (2017). Identification, chemical synthesis and heterologous expression of an antinociceptive peptide from the veined tree frog Trachycephalus typhonius. Process Biochemistry, 62, 205-214.

Hernandez-Vargas, M.J., Gil, J., Lozano, L., Pedraza-Escalona, M., Ortiz, E., Encarnacion-Guevara, S., Alagon, A., Corzo, G. (2017). Proteomic and transcriptomic analysis of saliva components from the hematophagous reduviid Triatoma pallidipennis. Journal of Proteomics, 162, 30-39.

Jimenez-Vargas, J.M., Quintero-Hernandez, V., Gonzalez-Morales, L., Ortiz, E., Possani, L.D. (2017). Design and expression of recombinant toxins from Mexican scorpions of the genus Centruroides for production of antivenoms. Toxicon, 128, 5-14 [Corrigendum 130 (2017) 126].

Romero-Gutierrez, T., Peguero-Sanchez, E., Cevallos, M.A., Batista, C.V.F., Ortiz, E., Possani, L.D. (2017). A Deeper Examination of Thorellius atrox Scorpion Venom Components with Omic Techonologies. Toxins (Basel), 9 (12), 399.

Sanchez-Reyez, A., Batista-Garcia, R.A., Valdes-Garcia, G., Ortiz, E., Perezgasga, L., Zarate-Romero, A., Pastor, N., Folch-Mallol, J.L. (2017). A Family 13 thioesterase isolated from an activated sludge metagenome: Insights into aromatic compounds metabolism. Proteins, 85 (7), 1222-1237.

Santibanez-Lopez, C.E., Cid-Uribe, J.I., Zamudio, F.Z., Batista, C.V.F., Ortiz, E., Possani, L.D. (2017). Venom gland transcriptomic and venom proteomic analyses of the scorpion Megacormus gertschi Diaz-Najera, 1966 (Scorpiones: Euscorpiidae: Megacorminae). Toxicon, 133, 95-109.

Estrada,G., Silva,A.O., Villegas,E., Ortiz,E., Beirao,P.S.L., Corzo,G. (2016). Heterologous expression of five disulfide-bonded insecticidal spider peptides. Toxicon, 119, 152-158.

Figueroa-Montiel,A., Ramos,M.A., Mares,R.E., Duenas,S., Pimienta,G., Ortiz,E., Possani,L.D., Licea-Navarro,A.F. (2016). In Silico Identification of Protein Disulfide Isomerase Gene Families in the De Novo Assembled Transcriptomes of Four Different Species of the Genus Conus. PLoS ONE, 11 (2), e0148390.

Santibanez-Lopez,C.E., Cid-Uribe,J.I., Batista,C.V., Ortiz,E., Possani,L.D. (2016). Venom Gland Transcriptomic and Proteomic Analyses of the Enigmatic Scorpion Superstitionia donensis (Scorpiones: Superstitioniidae), with Insights on the Evolution of Its Venom Components. Toxins (Basel), 8 (12), 367.

Ortiz,E., Gurrola,G.B., Schwartz,E.F., Possani,L.D. (2015). Scorpion venom components as potential candidates for drug development. Toxicon, 93, 125-135.

Ortiz,E. Possani,L.D. 2015. The unfulfilled promises of scorpion insectotoxins Journal of Venomous Animals and Toxins Including Tropical Diseases, 21, .

Zuniga-Navarrete,F. Gomez,I. Pena,G. Amaro,I. Ortiz,E. Becerril,B. Ibarra,J.E. Bravo,A. Soberon,M. 2015. Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12 Insect Biochemistry and Molecular Biology, 59, 50-57.

Quintero-Hernandez,V. Ramirez-Carreto,S. Romero-Gutierrez,M.T. Valdez-Velazquez,L.L. Becerril,B. Possani,L.D. Ortiz,E. 2015. Transcriptome Analysis of Scorpion Species Belonging to the Vaejovis Genus PLoS ONE, 10, e0117188.

Ortiz,E. Gurrola,G.B. Schwartz,E.F. Possani,L.D. 2015. Scorpion venom components as potential candidates for drug development Toxicon, 93, 125-135.

Ortiz,E. Rendon-Anaya,M. Rego,S.C. Schwartz,E.F. Possani,L.D. 2014. Antarease-like Zn-metalloproteases are ubiquitous in the venom of different scorpion genera Biochimica et Biophysica Acta (BBA), 1840, 1738-1746.

Gonzalez-Andrade,M. Becerril-Lujan,B. Sanchez-Lopez,R. Cecena-Alvarez,H. Perez-Carreon,J.I. Ortiz-Suri,E. Fernandez-Velasco,D.A. Del Pozo-Yauner,L. 2013. Mutational and genetic determinants of lambda6 light chain amyloidogenesis Febs Journal, 280, 6173-6183.

Corrales-Garcia,L. Ortiz,E. Castaneda-Delgado,J. Rivas-Santiago,B. Corzo,G. 2013. Bacterial expression and antibiotic activities of recombinant variants of human beta-defensins on pathogenic bacteria and M. tuberculosis Protein Expression and Purification, 89, 33-43.

Aguilar,M.B. Ortiz,E. Kaas,Q. Lopez-Vera,E. Becerril,B. Possani,L.D. de la Cotera,E.P. 2013. Precursor De13.1 from Conus delessertii defines the novel G gene superfamily Peptides, 41, 17-20.

Ramirez-Carreto,S. Quintero-Hernandez,V. Jimenez-Vargas,J.M. Corzo,G. Possani,L.D. Becerril,B. Ortiz,E. 2012. Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae Peptides, 34, 290-295.

Quintero-Hernandez,V. Ortiz,E. Rendon,M.R. Schwartz,E.F. Becerril,B. Corzo,G. Possani,L.D. 2011. Scorpion and spider venom peptides: Gene cloning and peptide expression Toxicon, 58, 644-663.

Estrada,G. Restano-Cassulini,R. Ortiz,E. Possani,L.D. Corzo,G. 2011. Addition of positive charges at the C-terminal peptide region of CssII; a mammalian scorpion peptide toxin; improves its affinity for sodium channels Nav1.6 Peptides, 32, 75-79 (Correction vol 32 p.1096).
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