Acceso a usuarios
Bienvenid@

Tutores

LETICIA MORENO FIERROS

Facultad de Estudios Superiores- Iztacala (FES-I)

Contacto

Teléfono: 55 56 23 13 33 Ext. 39786
Email: lemofi@unam.mx

Campos de conocimiento

Biología Molecular y Celular de Microorganismos, Plantas y Animales
Bioquímica
Biotecnología

Líneas de investigación

Inmunidad en Mucosas, Inmunobiología, vacunas, mecanismo inmunopotenciador de proteínas Cry1Ac de Bacillus thuringiensis, efecto adyuvante antitumoral de Cry1Ac, vacunas multiepitópicas hacia cancer de mama en VLPs quiméricas de VP2 de parvovirus B19,

Publicaciones

70) Torres-Martínez M, Rubio-Infante N, García-Hernández AL, Nava-Acosta R, Ilhuicatzi-Alvarado D, Moreno-Fierros L. Cry1Ac toxin induces macrophage activation via ERK1/2, JNK and p38 mitogen-activated protein kinases. Int J Biochem Cell Biol. 2016 Jul 6;78:106-115. doi: 10.1016/j.biocel.2016.06.022. [Epub ahead of print] PERGAMON-ELSEVIER SCIENCE LTD ENGLAND ISSN: 1357-2725. 5-Year Impact Factor: 4.172 , 3.2 actual Q2

73) Rubio-Infante N, Ilhuicatzi-Alvarado D, Torres-Martínez M, Reyes-Grajeda JP, Nava-Acosta R, González-González E, Moreno-Fierros L The macrophage activation induced by Bacillus thuringiensis Cry1Ac protoxin involves ERK1/2 and p38 pathways and the interaction with cell-surface-HSP70" Journal of Cellular Biochemistry 119(1) • June 2017 doi: 10.1002/jcb.26216. J Cell Biochem 2018 Jan;119(1):580-598.
doi: 10.1002/jcb.26216. Epub 2017 Jul 11. ISSN 1097-4644 FI 2.9 Q2

74) Cover Image, Volume 119, Number 1, January 2018.Rubio-Infante N, Ilhuicatzi-Alvarado D, Torres-Martínez M, Reyes-Grajeda JP, Nava-Acosta R, González-González E, Moreno-Fierros L.
J Cell Biochem. 2018 Jan;119(1):i. doi: 10.1002/jcb.26485.
75) KI Santos-Vigil, D Ilhuicatzi-Alvarado, AL García-Hernández, JS Herrera, L Moreno-Fierros Study of the allergenic potential of Bacillus thuringiensis Cry1Ac toxin following intra-gastric administration in a murine model of food-allergy International Immunopharmacology 61, 185-196 2018doi: 10.1016/j.intimp.2018.05.029. Epub 2018 Jun 7. FI 3.11 Q2 1567-5769
76) Luna-Pineda VM, Ochoa SA, Cruz-Córdova A, Cázares-Domínguez V, Reyes-Grajeda JP, Flores-Oropeza MA, Arellano-Galindo J, Castro-Hernández R, Flores-Encarnación M, Ramírez-Vargas A, Flores-García HJ, Moreno-Fierros L, Xicohtencatl-Cortes J. Features of urinary Escherichia coli isolated from children with complicated and uncomplicated urinary tract infections in Mexico. PLoS One. 2018 Oct 4;13(10):e0204934. doi: 10.1371/journal.pone.0204934. eCollection 2018. PUBLIC LIBRARY SCIENCE, 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA ISSN: 1932-6203 FI 2.76 Q1
79) Salazar-González JA, Ruiz-Cruz AA, Bustos-Jaimes I, Moreno-Fierros L. Expression of Breast Cancer-Related Epitopes Targeting the IGF-1 Receptor in Chimeric Human Parvovirus B19 Virus-Like Particles. Mol Biotechnol. 2019 Oct;61(10):742-753. doi: 10.1007/s12033-019-00198-y. 2019 Epub Jul 17..
80) Victor Manuel Luna-Pineda, Leticia Moreno-Fierros, Vicenta Cazares- Dominguez, Damaris Ilhuicatzi-Alvarado, SARA A. OCHOA, Ariadnna Cruz-Córdova, Pedro Valencia-Mayoral, Juan Xicohtencatl-Cortes, Alejandra Rodríguez-Leviz Curli of Uropathogenic Escherichia coli Enhance Urinary Tract Colonization as a Fitness Factor. Front Microbiol. 2019 Sep 3;10:2063. doi: 10.3389/fmicb.2019.02063. eCollection 2019. In press 2019
81) Jiménez-Chávez ÁJ, Moreno-Fierros L, Bustos-Jaimes I. Therapy with multi-epitope virus-like particles of B19 parvovirus reduce tumor growth and lung metastasis in an aggressive breast cancer mouse model. Vaccine. 2019 Nov 20;37(49):7256-7268. doi: 10.1016/j.vaccine.2019.09.068. Epub 2019 Sep 27.
82) Moreno-Fierros L, García-Silva I, Rosales-Mendoza S.Development of SARS-CoV-2 vaccines: should we focus on mucosal immunity?Expert Opin Biol Ther. 2020 May 7. doi: 10.1080/14712598.2020.1767062. 831-836
83) Bautista-Jacobo I, Rubio-Infante N, Ilhuicatzi-Alvarado D, Moreno-Fierros L
Bacillus thuringiensis Cry1Ac toxin and protoxin do not provoke acute or chronic cytotoxicity on macrophages and leukocytes 2020 DOI : 10.1007/s11626-020-00525-7 In Vitro Cell.Dev.Biol.-Animal (2021) 57:42-52
87 Ángel de Jesús Jiménez-Chávez, Brenda Katherine Nava-García, Ismael Bustos Jaimes, Leticia Moreno-Fierros, B19-VLPs as an effective delivery system for tumour antigens to induce humoral and cellular immune responses against triple negative breast cancer, Immunology Letters, 2021,
34329616
ISSN 0165-2478, https://doi.org/10.1016/j.imlet.2021.09.002
88 Servin-Garrido RR, Ilhuicatzi-Alvarado D, Jiménez-Chávez ÁJ, Moreno-Fierros L. Cry1Ac Protoxin Confers Antitumor Adjuvant Effect in a Triple-Negative Breast Cancer Mouse Model by Improving Tumor Immunity. Breast Cancer (Auckl). 2022 Jan 5;16:11782234211065154. doi: 10.1177/11782234211065154. PMID: 35002244; PMCID: PMC8738886.
ISSN: 1178-2234 impact factor 1.95

84) Ibarra-Moreno CD, Ilhuicatzi-Alvarado D, Moreno-Fierros L. Differential capability of Bacillus thuringiensis Cry1Ac protoxin and toxin to induce in vivo activation of dendritic cells and B lymphocytes. Dev Comp Immunol. 2021 Mar 22;121:104071. doi: 10.1016/j.dci.2021.104071. Epub ahead of print. PMID: 33766585. Impact factor 3.192

89 A systematic review and meta-analysis of the IgA seroprevalence in COVID-19 patients: Is there a role for IgA in COVID-19 diagnosis or severity?
Rangel-Ramírez VV, Macías-Piña KA, Servin-Garrido RR, de Alba-Aguayo DR, Moreno-Fierros L, Rubio-Infante N. Microbiol Res. 2022 Jun 30;263:127105. doi: 10.1016/j.micres.2022.127105. Online ahead of print. PMID: 35816990 Microbiol Res. 2022 Oct;263:127105.
90 Jiménez-Chavez AJ and Moreno Fierros L Nonenveloped Virus-Like Particles: A Promising Antigen-Delivery Strategy for the Induction of Antitumor Immune Responses Nano LIFE 2022) 2230004 DOI: 10.1142/S1793984422300047

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx
UNAM Posgrado