Identificación de compuestos con actividad bactericida o anti-virulencia contra cepas multi-resistentes a antibióticos de las bacterias patógenas ESKAPE (Enterococcus spp., Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanni, Pseudomonas aeruginosa y Enterobacter spp.).

Mecanismos moleculares que controlan la expresión de genes de virulencia e identificación de nuevos factores de virulencia de Salmonella.

Publicaciones

50.- Nava-Galeana, J., Núñez, C.E, and Bustamante, V.H. (2023). Proteomic analysis reveals the global effect of the BarA/SirA-Csr regulatory cascade in Salmonella Typhimurium grown in conditions that favor the expression of invasion genes. Journal of Proteomics. 104960. doi: 10.1016/j.jprot.2023.104960.
Factor de impacto de la revista: 3.855

49.- Romero-González, L.E., Rojas-Vargas, J., Muriel-Millán, L.F., Bustos-Martínez, J.A., Bustamante, V.H.*, and Pardo-López, L.* (2023). Genomic and phenotypic characterization of Pseudomonas sp. GOM7, a novel marine bacterial species with antimicrobial activity against multidrug-resistant Staphylococcus aureus. PLoS One. 18(7):e0288504. doi: 10.1371/journal.pone.0288504. eCollection 2023.
*Autores para correspondencia.
Factor de impacto de la revista: 3.752

48.- Nava-Galeana, J., Yakhnin, H., Babitzke, P., and Bustamante, V.H. (2023). CsrA positively and directly regulates the expression of the pdu and eut genes required for luminal replication of Salmonella Typhimurium. Microbiology Spectrum. e0151623. doi: 10.1128/spectrum.01516-23.
Factor de impacto de la revista: 9.043

47.- Gallegos-Monterrrosa, R., Orozco-Mendiola, R., Núñez, Y., Auvynet, C., Kesarla, M., Tang, B., Ruíz-Ortega, L.I.*, and Bustamante, V.H.* (2023). Antibacterial and antibiofilm activities of ZIF-67. Journal of Antibiotics. doi: 10.1038/s41429-023-00637-8.
*Autores para correspondencia.
Factor de impacto de la revista: 3.424

46.- Arista-Regalado, A., Barba-León, J., Bustamante, V.H., Flores-Valdéz, M., J. Gaona, and Fajardo-Guerrero, M. (2023). hilD is required for the active internalization of Salmonella Newport into cherry tomatoes. Journal of Food Protection. 86 (5): 1000085. doi: 10.1016/j.jfp.2023.100085.
Factor de impacto de la revista: 2.753

45.- Pérez-Morales, D., and Bustamante, V.H. (2023). Disarming the pathogen. News  Views. Nature Chemical Biology. 19:5-6. doi: 10.1038/s41589-022-01133-0.
Factor de impacto de la revista: 16.174

44.- Caspeta, L., and Bustamante, V.H. (2022). Inducing self-poisoning: a feasible antibacterial strategy?. Commentary. Journal of Bacteriology. 204(12):e0041122. doi: 10.1128/jb.00411-22.
Factor de impacto de la revista: 3.476

43.- Banda, M.M., Pérez-Morales, D., Zavala-Alvarado, C., Nava-Galeana, J., and Bustamante, V.H. (2022). Two additional connections between the transcriptional programs controlling invasion and intracellular replication of Salmonella: HilD-SprB positively regulates phoP and slyA. Journal of Bacteriology. 204(11):e0020422. doi: 10.1128/jb.00204-22.
Factor de impacto de la revista: 3.476

42.- León-Montes, N., Nava-Galeana, J., Rodríguez-Valverde, D., Soria-Bustos, J., Rosales-Reyes, R., Ares, M.A., Rivera-Gutiérrez, S., Hirakawa, H., Bustamante, V.H.*, and De la Cruz, M.A.* (2022). The two-component system CpxRA represses Salmonella pathogenicity island 2 by directly acting on the ssrAB regulatory operon. Microbiology Spectrum e0271022. doi: 10.1128/spectrum.02710-22.
*Autores para correspondencia.
Factor de impacto de la revista: 9.043

41.- Valdespino-Díaz, M.A., Rosales-Reyes, R., De la Cruz, M.A., and Bustamante, V.H. (2022). Regulatory evolution of the phoH ancestral gene in Salmonella enterica serovar Typhimurium. Journal of Bacteriology. 204(5):e0058521. doi: 10.1128/jb.00585-21.
Factor de impacto de la revista: 3.476

40.- Valdez-Salazar, H.A., Ares, M.A., Fernández, F.J., Ibarra, J.A., Torres, J., Bustamante, V.H., and De la Cruz, M.A. (2021). Long-chain fatty acids alter transcription of Helicobacter pylori virulence and regulatory genes. PeerJ. 9:e12270. doi: 10.7717/peerj.12270.
Factor de impacto de la revista: 2.984

39.- Pérez-Morales, D., Nava-Galeana, J., Rosales-Reyes, R., Teehan, P., Yakhnin, H., Melchy-Pérez, E.I., Rosenstein, Y.J., De la Cruz, M.A., Babitzke, P., and Bustamante, V.H. (2021). An incoherent feedforward loop formed by SirA/BarA, HilE and HilD is involved in controlling the growth cost of virulence factor expression by Salmonella Typhimurium. PLoS Pathogens. 17(5):e1009630. doi: 10.1371/journal.ppat.1009630.
Factor de impacto de la revista: 6.823

38.- Pérez-Morales, D., and Bustamante, V.H. (2021). Cross-kingdom metabolic manipulation promotes Salmonella replication inside macrophages. Comment. Nature Communications. 12(1):1862. doi: 10.1038/s41467-021-22198-w.
Factor de impacto de la revista: 14.919

37.- Chau, N.Y.E., Pérez-Morales, D., Elhenawy, W., Bustamante, V.H., Zhang, Y.E., and Coombes, B.K. (2021). (p)ppGpp-dependent regulation of PpnNST confers complement resistance by Salmonella Typhimurium. Infection and Immunity. IAI.00639-20. doi: 10.1128/IAI.00639-20.
Factor de impacto de la revista: 3.441

36.- Romero-González, L.E., Pérez-Morales, D., Paredes-Hernández, D.A., Vázquez-Guerrero, E., Estrada-de los Santos, P., Villa-Tanaca, L., De la Cruz, M.A., Bustamante, V.H., and Ibarra, J.A. (2020). The Salmonella Typhimurium InvF-SicA complex is required for transcription of target genes even in the absence of repressor H-NS. PLoS One. 15:e0240617. doi: 10.1371/journal.pone.0240617.
Factor de impacto de la revista: 3.240

35.- Rivera-Mendoza, D., Martínez-Flores, I., Santamaría, R.I., Lozano, L., Bustamante, V.H.*, and Pérez-Morales, D.* (2020). Genomic analysis reveals the genetic determinants associated with antibiotic resistance in the zoonotic pathogen Campylobacter spp. distributed globally. Frontiers in Microbiology. 11:513070. doi: 10.3389/fmicb.2020.513070.
*Autores para correspondencia.
Factor de impacto de la revista: 5.640

34.- Banda, M.M., Manzo, R., and Bustamante, V.H. (2019). HilD induces expression of a novel Salmonella Typhimurium invasion factor, YobH, through a regulatory cascade involving SprB. Scientific Reports. 9(1):12725. doi: 10.1038/s41598-019-49192-z.
Factor de impacto de la revista: 3.998

33.- Banda, M.M., Zavala-Alvarado, C., Pérez-Morales, D., and Bustamante, V.H. (2019). SlyA and HilD counteract H-NS-mediated repression on the ssrAB virulence operon of Salmonella Typhimurium and thus promote its activation by OmpR. Journal of Bacteriology. JB.00530-18. doi: 10.1128/JB.00530-18.
Factor de impacto de la revista: 3.006

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx