Mecanismos moleculares que regulan la interacción patógeno-célula hospedera y el desarrollo de enfermedades infecciosas.

Mecanismos moleculares que activan y regulan el proceso inflamatorio que instiga el desarrollo de enfermedades crónicas, tanto en la periferia como en el sistema nervioso central.

Mecanismos moleculares que median la comunicación entre el sistema nervioso central y el sistema inmune.

Publicaciones

1.-Licea-Cejudo RC, Arenas-Salgado LK, Salazar-León J, Martínez-Martínez MV, Carreón-Rodríguez A, Pedraza-Alva G, and Pérez-Martínez L. (2020). Physical activity attenuates telomere shortening in male children with a high body fat percentage. Acta Pediatrica.
2.-Sánchez Nilda C, Medrano-Jiménez E, Aguilar-León E, Pérez-Martínez L, and Pedraza-Alva G. (2019) TNF-induced miR-146a upregulation promotes human lung adenocarcinoma metastasis by targeting Merlin. DNA and Cell Biology.
3.-Salazar-Leon,J. Valdez-Hernandez,A.L. Garcia-Jimenez,S. Roman-Dominguez,L. Huanosta-Murillo,E. Bonifaz,L.C. Perez-Martinez,L. Pedraza-Alva,G. (2019) Nlrp1b1 negatively modulates obesity-induced inflammation by promoting IL-18 production. Scientific Reports, 9, 13815.
4.-Ramirez-Serrano,C.E. Jimenez-Ferrer,E. Herrera-Ruiz,M. Zamilpa,A. Vargas-Villa,G. Ramirez-Carreto,R.J. Chavarria,A. Tortoriello,J. Pedraza-Alva,G. Perez-Martinez,L. (2019) A Malva parviflora's fraction prevents the deleterious effects resulting from neuroinflammation. Biomedicine and Pharmacotherapy, 118, 109349.
5.-Medrano-Jiménez E, Jiménez-Ferrer Carrillo I, Pedraza-Escalona M, Ramírez-Serrano CE, Álvarez-Arellano L, Cortés-Mendoza J, Herrera-Ruiz M, Jiménez-Ferrer E, Zamilpa A, Tortoriello J, Pedraza-Alva G, Pérez-Martínez L. (2019) Malva parviflora extract ameliorates the deleterious effects of a high fat diet on the cognitive deficit in a mouse model of Alzheimer's disease by restoring microglial function via a PPAR-γ-dependent mechanism. J Neuroinflammation.16: 143. PMID:31291963
6.-Villaseñor T, Madrid-Paulino E, Maldonado-Bravo R, Pérez-Martínez L, Pedraza-Alva G. (2019) Mycobacterium bovis BCG promotes IL-10 expression by establishing a SYK/PKCα/β positive autoregulatory loop that sustains STAT3 activation. Pathog Dis. 2019 Apr 1;77(3). pii: ftz032. PMID:31175361
7.-Ramírez-Carreto S, Pérez-García EI, Salazar-García SI, Bernáldez-Sarabia J, Licea-Navarro A, Rudiño-Piñera E, Pérez-Martínez L, Pedraza-Alva G, Rodríguez-Almazán C. (2019) Identification of a pore-forming protein from sea anemone Anthopleura dowii Verrill (1869) venom by mass spectrometry. J Venom Anim Toxins Incl Trop Dis. 11;25:e147418. PMID:31131002
8.-Pedraza-Alva G, Ramírez-Serrano CE, Pedraza F, Flores-Vallejo RDC, Villarreal ML, Pérez-Martínez L. (2019) From traditional remedies to cutting-edge medicine: Using ancient mesoamerican knowledge to address complex disorders relevant to psychoneuroimmunology.
Brain Behav Immun. 79:3-5. PMID:30980951
9.-Villasenor,T. Madrid-Paulino,E. Maldonado-Bravo,R. Urban-Aragon,A. Perez-Martinez,L. Pedraza-Alva,G. (2017) Activation of the Wnt Pathway by Mycobacterium tuberculosis: A Wnt-Wnt Situation. Frontiers in Immunology, 8, 50. ISSN:1664-3224
10.-Álvarez-Arellano L, Pedraza-Escalona M, Blanco-Ayala T, Camacho-Concha N, Cortez-Mendoza C, Pérez-Martínez L, and Pedraza-Alva G. (2017) Autophagy impairment by caspase-1-dependente inflammation mediates memory loss in response to β-Amyloid peptides accumulation. J Neurosci. Res. doi: 10.1002/jnr.24130.
11.-Villasenor,T. Madrid-Paulino,E. Maldonado-Bravo,R. Urban-Aragon,A. Perez-Martinez,L. Pedraza-Alva,G. (2017) Activation of the Wnt Pathway by Mycobacterium tuberculosis: A Wnt-Wnt Situation Frontiers in Immunology, 8, 50. ISSN:1664-3224
12.-Torres-Huerta A, Villaseñor-Toledo T, Parada C, López O, Espitia C, Pedraza-Alva G, and Rosenstein Y. (2017) The interaction of the CD43 sialomucin with the Mycobacterium Tuberculosis CPN60.2 Chaperonin mediates macropahge TNF-α production. Infect Immun. Jan 9. pii: IAI.00915-16. doi: 10.1128/IAI.00915-16. ISSN: 0019-9567
13.-Bravo-Adame ME, Vera-Estrella R, Barkla BJ, Martínez-Campos C, Flores-Alcantar A, Ocelotl-Oviedo JP, Pedraza-Alva G, and Rosenstein, Y. (2017) An alternative mode of CD43 signal transduction activates pro-survival pathways of T lymphocytes. Immunology. Jan;150(1):87-99. doi: 10.1111/imm.12670. ISSN:0019-2805
14.- Pérez-García EI, Meza-Sosa KF, López-Sevilla Y, Camacho-Concha N., Sánchez NC, Pérez-Martínez L, and Pedraza-Alva, G. (2015) Merlin negative regulation by miR-146a promotes cell transformation. BBRC. DOI 10.1016/j.bbrc.2015.10.156. ISSN:0006-291X
15.- Pedraza-Alva G, Pérez-Martínez L, Valdez-Hernandez L, Meza-Sosa KF, and Ando-Kuri M (2015) Negative regulation of the inflammasome: keeping inflammation under control. Immunological Reviews. 265: 231-257. ISSN:0105-2896

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx