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Bienvenid@

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PATRICIA OSTROSKY-WEGMAN SHEJET

Instituto de Investigaciones Biomédicas (IIB)

Contacto

Teléfono: 55 56 22 3846
Email: ostrosky@unam.mx
Sitio web: Visitar sitio web

Campos de conocimiento

Farmacología
Genética y Fisiología Celular

Líneas de investigación

Toxicología genética

Publicaciones

Fernández-Rojas MA, Ávila G, Romero-Valdovinos M, Plett-Torres T, Salazar AM, Sordo M, Chávez-Vargas M, Coeto Ángeles CJ, Cruz-Rivera M Santiago-Olivares C, Ramírez Hinojosa JP, Maravilla P, Flisser A, Ostrosky-Wegman P, Mendlovic F. Elevated levels of cytotoxicity, cytokines, and anti-SARS-CoV-2 antibodies in mild cases of COVID-1. Viral Immunology Aceptado. 2023 July. FI: 2.2

Vergara-Gerónimo CA, León-Del-Rio A, Rodríguez-Dorantes M, Camacho-Carranza R, Ostrosky-Wegman P and Salazar AM . Arsenic reduces the GATA3 expression associated with an increase in proliferation and migration of mammary epithelial cell line MCF-10A. Toxicology and Applied Pharmacology 472:116573-116581. 2023 FI: 4.0
Cortés-Ramírez SA, Salazar AM, Sordo M, Ostrosky-Wegman P, Morales-Pacheco M, Cruz-Burgos M, Losada-García A, Rodríguez-Martínez G, González-Ramírez I, Vazquez-Santillan K, González-Covarrubias V, Maldonado-Lagunas V and Rodríguez-Dorantes M. Transcriptome-Wide analysis of low-concentration exposure to bisphenol A, S, and F in prostate cancer cells. International Journal of Molecular Sciences 24: 9462-9481. 2023 FI: 6.2
Pánico P, Velasco M, Salazar AM, Ostrosky-Wegman P and Hiriart M. The effects of sucrose and arsenic on muscular insulin signaling pathways differ between the gastrocnemius and quadriceps muscles. Frontiers in Endocrinology 14:1165415-1165428. 2023 FI: 5.9 Carlos-Escalante JA, Mejía-Pérez SI, Soto-Reyes E, Guerra-Calderas L, Cacho-Díaz B, Torres-Arciga K, Montalvo-Casimiro M, González-Barrios R, Reynoso-Noverón N, Ruiz-de la Cruz M, Díaz-Velásquez CE, Vidal-Millán S, Álvarez-Gómez RM, Sánchez-Correa TE, Pech-Cervantes CH, Soria-Lucio JA, Pérez-Castillo A, Salazar AM, Arriaga-Canon C, Vaca-Paniagua F, González-Arenas A, Ostrosky-Wegman P, Mohar-Betancourt A, Herrera LA, Corona T and Wegman-Ostrosky T. Deep DNA sequencing of MGMT, TP53 and AGT in Mexican astrocytoma patients identifies an excess of genetic variants in women and a predictive biomarker. Journal of Neuro-Oncology. 161:165-174. 2022. FI: 4.1


Pánico P, Velasco M, Salazar AM, Picones A, Ortiz-Huidobro RI, Guerrero-Palomo G, Salgado-Bernabé ME, Ostrosky-Wegman P and Hiriart M. Is arsenic exposure a risk factor for metabolic syndrome? A review of the potential mechanisms. Frontiers in Endocrinology 13:878280-878304. 2022. FI: 5.9

Pánico P, Ostrosky-Wegman P and Salazar AM (corresponding author). The potential role of COVID-19 in the induction of DNA damage. Mutation Research - Reviews in Mutation Research 789:108411-108419. 2022. FI: 6.1

Vergara-Gerónimo C, León Del Río A, Rodríguez-Dorantes M, Ostrosky-Wegman P and Salazar AM . Arsenic-protein interactions as a mechanism of arsenic toxicity. Toxicology and Applied Pharmacology 431: 115738-115746. 2021. FI: 4.0

Muñoz-Rodríguez A, Maciel-Ruiz JA, Salazar AM, Sordo M, Ostrosky-Wegman P, Limón-Pacheco JH, Nepomuceno-Hernández AE, Ayala-Yáñez R, Gonsebatt ME and Osorio-Yáñez C. Prenatal particulate matter (PM) exposure and natriuretic peptides in newborns from Mexico City. International Journal of Environmental Research and Public Health 18: 6546-6554. 2021. FI: 4.799

Salazar AM, Sordo M, Navarrete-Monroy E, Pánico P, Díaz-Villaseñor A, Montúfar-Chaveznava R, Caldelas I and Ostrosky-Wegman P. Maternal overnutrition before and during pregnancy induces DNA damage in male offspring: A rabbit model. Mutation Research (Genetic Toxicology and Environmental Mutagenesis) 865: 503324-503332. 2021. FI: 2.3

Pánico P, Hiriart M, Ostrosky-Wegman P and Salazar AM . TUG is a calpain-10 substrate involved in the translocation of GLUT4 in adipocytes. Journal of Molecular Endocrinology 65: 45-57. 2020. FI: 5.1

Navarrete E, Díaz-Villaseñor A, Díaz G, Salazar AM, Montúfar-Chaveznava R, Ostrosky-Wegman P and Caldelas I. Misadjustment of diurnal expression of core temperature and locomotor activity in lactating rabbits associated with maternal over-nutrition before and during pregnancy. PLoS One 15: e0232400- e0232428. 2020. FI: 3.8

Sordo M, Maciel-Ruiz JA, Salazar AM, Robles-Morales R, Veloz-Martínez MG, Pacheco-Limón JH, Nepomuceno-Hernández AE, Ayala-Yáñez R, Gonsebatt ME and Ostrosky-Wegman P. Particulate matter-associated micronuclei frequencies in maternal and cord blood lymphocytes. Environmental and Molecular Mutagenesis 60: 421-427. 2019. FI: 3.7

Maciel-Ruiz JA, López-Rivera C, Robles-Morales R, Veloz-Martínez MG, López-Arellano R, Rodríguez-Patiño G, Petrosyan P, Govezensky T, Salazar AM, Ostrosky-Wegman P, Montero-Montoya R and Gonsebatt ME. Prenatal exposure to particulate matter and ozone: Bulky DNA adducts, plasma isoprostanes, allele risk variants, and neonate susceptibility in the Mexico City Metropolitan Area. Environmental and Molecular Mutagenesis 60: 428-442. 2019. FI: 3.7


Salazar AM, Pánico P, Burns AL, Díaz-Villaseñor A, Torres-Arellano JM, Juárez-Nájera A, González-Pimienta RE, Alvarez-Sekely AM, Zacarías-Castillo R and Ostrosky-Wegman P. Calpain activity in leukocytes is associated with diabetes biochemical markers. Archives of Medical Research 50: 451-460. 2019. FI: 5.1
Paredes-Céspedes DM, Herrera-Moreno JF, Bernal-Hernández YY, Medina-Díaz IM, Salazar AM, Ostrosky-Wegman P, Barrón-Vivanco BS and Rojas-García AE. Pesticide exposure modifies DNA methylation of coding region of WRAP53α, an antisense sequence of p53, in a mexican population. Chemical Research in Toxicology 32: 1441-1448. 2019. FI: 3.9
Pánico P, Juárez-Nájera A, Iturriaga-Goyon E, Ostrosky-Wegman P, Salazar AM Arsenic impairs GLUT1 trafficking through the inhibition of the calpain system in lymphocytes. Toxicology and Applied Pharmacology. 380:114700. 2019. FI: 4.0


Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx
UNAM Posgrado