Contacto
Líneas de investigación
Mecanismos de muerte neuronal programada.
Papel de las especies reactivas de oxígeno en la muerte y diferenciación neuronal.
Papel de la NADPH-oxidasa en la muerte y desarrollo neuronal.
Publicaciones
Zaragoza-Campillo M.A. and Morán J Reactive oxygen species evoked by potassium deprivation and staurosporine inactivate Akt and induce the expression of TXNIP in cerebellar granule neurons. Oxidative Medicine and Cellular Longevity. Volume 2017:8930406, doi.org/10.1155/2017/8930406 (2017)
Olguín-Albuerne, M. and Morán J. Redox signaling mechanisms in nervous system development. Antioxidants & Redox Signaling. 28(18):1603-1625. DOI: 10.1089/ars.2017.7284 (2017)
Cid-Castro C., Hernández-Espinosa DR., Morán J. ROS as regulators of mitochondrial dynamics in neurons. Cell Molecular and Neurobiology. 38(5):995-1007. doi: 10.1007/s10571-018-0584-7 (2018)
Benítez-Guzmán, A., Arriaga-Pizano, L., Morán, J. and Gutiérrez-Pabello, J. Endonuclease G takes part in AIF-mediated caspase-independent apoptosis in Mycobacterium bovis-infected bovine macrophages. Veterinary Research. 49(1):69. doi: 10.1186/s13567-018-0567-1. (2018).
Maciel-Rivera A, Flores-Villalva S, Jímenez-Vázquez I, Catalán-Barcenas O, Espitia-Pinzón CI, Morán J, Arriaga-Pizano L, Benítez-Guzmán A, Alfonseca-Silva E, Gutiérrez-Pabello JA. Mycobacterium tuberculosis and Mycobacterium bovis derived proteins induce caspase-independent apoptosis in bovine macrophages. Veterinaria México OA. 6(1). doi: 10.22201/fmvz.24486760e.2019.1.560. (2019).
Hernández-Espinosa, D.R., Massieu, L., Montiel , T. and Morán J. Role of NADPH oxidase 2 in the progression of the inflammatory response secondary to excitotoxic damage. Journal of Neuroinflammation 16:91. doi.org/10.1186/s12974-019-1478-4 (2019).
Benítez-Rangel E., Olguín-Albuerne M., López-Méndez M.C., Domínguez-Macouzet G., Guerrero-Hernández A. and Morán J. Caspase-3 activation correlates with the initial mitochondrial membrane depolarization in neonatal cerebellar granule neurons. Frontiers in Cell and Developmental Biology 8:544. doi: 10.3389/fcell.2020.00544 (2020).
Altamirano-Bustamante NF, Garrido-Magaña E, Morán E, Calderón A, Pasten-Hidalgo K,
Castillo-Rodríguez RA, Rojas G, Lara-Martínez R., Leyva-García E., Larralde-Laborde M.,
Domínguez-Macouzet G., Murata Ch., Margarita-Vázquez Y., Payro R., Barbosa M., Valderrama A., Montesinos H., Domínguez-Camacho A., García-Olmos V., Ferrer R., Medina-Bravo P., Santoscoy F., Revilla-Monsalve C., Jiménez-García L.F., Morán J., Vilalobos-Alva J., Villalobos M.J., Calzada-León R., Altamirano P., Altamirano-Bustamante M. Protein-conformational diseases in childhood: Naturally occurring hIAPP amyloid-oligomers and early β-
cell damage in obesity and diabetes. PLoS ONE 15(8): e0237667. https://doi.org/10.1371/journal.pone.0237667 (2020).
Valeria Rodriguez-Chavez, Gladys Molina-Salinas, Wendy Andrea Zepeda-Ruiz, Maria Carmen Rodriguez, Julio Moran, Ofir Picazo, Marco Cerbon. Participation of glutamatergic ionotropic receptors in excitotoxicity: the neuroprotective role of prolactin. Neuroscience. 2021 May 1;461:180-193. doi: 10.1016/j.neuroscience.2021.02.027
Cid-Castro C. and Morán J. Differential ROS-mediated phosphorylation of Drp1 in mitochondrial fragmentation induced by distinct apoptotic stimuli in cerebellar granule neurons. Oxidative Medicine and Cellular Longevity. 2021 Apr 13;2021:8832863. doi: 10.1155/2021/8832863. eCollection 2021.
Morales-Rosales Sandra Lizbeth, Santín-Márquez Roberto, Posadas-Rodriguez Pedro, Rincon-Heredia Ruth3, Montiel Teresa, Librado-Osorio Raúl, Luna-López Armando, Rivero-Segura Nadia Alejandra, Torres Claudio, Cano-Martínez Agustina, Silva-Palacios Alejandro, Cortés-Hernández Paulina, Morán-Andrade Julio, Massieu Lourdes, Konigsberg Mina. Senescence in primary rat astrocytes induces loss of the 1 mitochondrial membrane potential and alters mitochondrial dynamics in cortical neurons. Frontiers in Aging Neuroscience. En prensa. 2021
