Ingeniería metabólica, biología sintética, bioingeniería y procesos de fermentación con microorganismos y microalgas para obtener biocombustibles y precursores de biopolímeros, a partir de azúcares de residuos agroindustriales. Cultivos auto, mixo y heterotróficos con microalgas extremófilas.

Publicaciones

(118) Pesce G. R., Alves-Ferreira J., Hsiao A., Torrado I., Martinez A., Mauromicale G. and Fernandes M. C. Bioethanol Production from Globe Artichoke Residues: from the Field to the Fermenter. BioEnergy Research. In Press. Nov 2022. http://doi.org/10.1007/s12155-022-10548-5. Print ISSN 19391234.
(117) Sierra-Ibarra E., Vargas-Tah A., Moss-Acosta C. L., Trujillo-Martínez B., Molina-Vázquez E. R., Rosas-Aburto A., Valdivia-López A., Hernández-Luna M. G., Vivaldo-Lima E. and Martinez A. Co-Fermentation of Glucose-Xylose Mixtures from Agroindustrial Residues by Ethanologenic Escherichia coli: A Study on the Lack of Carbon Catabolite Repression in Strain MS04. Molecules. In Press December 2022. https://doi.org/10.3390/. EISSN:14203049
(116) Fragoso-Jiménez Juan Carlos, Gutiérrez Rosa, Flores Noemí, Martínez Alfredo, Lara Alvaro, Delvigne Frank, Guillermo Gosset. Glucose consumption rate-dependent transcriptome profiling of Escherichia coli provides insight on performance as microbial factories Microbial Cell Factories. 21:189. 2022. Electronic ISNN 14752859.
(115) Rodríguez-Ochoa José Ignacio, Fragoso-Jiménez Juan Carlos, Flores Noemí, Martínez Luz María, Francisco Bolivar, Alfredo Martinez, Guillermo Gosset, Global transcriptomic response of Escherichia coli to p-coumaric acid. Microbial Cell Factories. 21:148. 2022. https://doi.org/10.1186/s12934-022-01874-6. Electronic ISNN 14752859.
(114) Ochoa-Chacón Alfayuset; Ramos-Valdivia Ana C.; Poggi-Varaldo Héctor Mario; Villa-Tanaca Lourdes; Martinez Alfredo; Ponce‑Noyola Teresa. Fermentation performance of a Mexican native Clavispora lusitaniae strain for xylitol and ethanol production from xylose, glucose and cellobiose. Enzyme and Microbial Technology 160: 110094, 2022. https://doi.org/10.1016/j.enzmictec.2022.110094. ISSN: 0141-0229. IF 3.705
(113) Vera-López Portillo F., Sierra-Ibarra E., Vera-Estrella R., Revah S., Ramírez O.T., Caspeta L, Martinez A. Growth and phycocyanin production with Galdieria sulphuraria UTEX 2919 using xylose, glucose, and corn stover hydrolysates under heterotrophy and mixotrophy. Algal Research. 65: 102752, 2022. https://doi.org/10.1016/j.algal.2022.102752. ISSN: 22119264. IF 4.401
(112) Montenegro-Herrera C. A., Vera-López Portillo Francisco, Hernández-Chávez Georgina T., Martínez Alfredo. Single-cell protein production potential with the extremophilic red microalgae Galdieria sulphuraria: growth and biochemical characterization. Journal of Applied Phycology. 34:1341-1352, 2022. https://doi.org/10.1007/s10811-022-02733-y. Electronic ISSN: 15735176, Print ISSN 09218971. IF 3.215.
(111) Wagner Evelyn, Sierra-Ibarra Estefanía, Rojas Natalia L.; Martinez Alfredo. One-pot bioethanol production from brewery spent grain using the ethanologenic Escherichia coli MS04. Renewable Energy. 189:717-725. 2022. https://doi.org/10.1016/j.renene.2022.03.014. ISNN 09601481.
(110) Alves-Ferreira J., Carvalheiro F, Duarte L.C, Ferreira A.R.P., Martinez A., Pereira H., Fernandes M.C. D-Lactic acid production from Cistus ladanifer residues: co-fermentation of pentoses and hexoses by Escherichia coli JU15. Industrial Crops & Products. 177:114519. 2022. https://doi.org/10.1016/j.indcrop.2022.114519. Electronic ISNN 09266690.
(109) Fernandes M.C, Alves-Ferreira J, Duarte LC, Pereira H, Carvalheiro F, Martinez A. D-Lactic acid production from hydrothermally pretreated, alkali delignified and enzymatically saccharified rockrose with the metabolic engineered Escherichia coli strain JU15. Biomass Conversion and Biorefinery. 2022:1-10. 2022. https://doi.org/10.1007/s13399-021-02207-0. Electronic ISSN 21906823.
(108) Salas-Navarrete Prisciluis C., Montes de Oca Miranda Arturo I., Alfredo Martinez, Luis Caspeta. Evolutionary and reverse engineering to increase Saccharomyces cerevisiae tolerance to acetic acid, acidic pH, and high temperature. Applied Microbiology and Biotechnology. 106:383-399. 2022. https://doi.org/10.1007/s00253-021-11730-z. Electronic ISNN 14320614. Print ISSN 01757598.
(107) Sierra-Ibarra Estefanía, Alcaraz-Cienfuegos Jorge, Vargas-Tah Alejandra, Rosas-Aburto Alberto, Valdivia-López Ángeles, Hernández-Luna Martín G., Vivaldo-Lima Eduardo, Martinez Alfredo. Ethanol production by Escherichia coli from detoxified lignocellulosic teak wood hydrolysates with high concentration of phenolic compounds. Journal of Industrial Microbiology & Biotechnology. 49 (2): kuab077. 2022. https://doi.org/10.1093/jimb/kuab077. Online ISNN 14765535 Print ISSN: 13675435.
(106) Ochoa-Chacón Alfayuset, Alfredo Martinez, Poggi-Varaldo Héctor Mario, Villa-Tanaca Lourdes, Ramos-Valdivia Ana C, Ponce-Noyola Teresa. Xylose metabolism in bioethanol production: Saccharomyces cerevisiae vs non-Saccharomyces yeasts. BioEnergy Research. 15:905-923. 2022. https://doi.org/10.1007/s12155-021-10340-x.Online ISSN 19391242. Print ISSN 19391234.
(105) Caspeta Luis, Kerkhoven Eduard J., Martinez Alfredo, Nielsen Jens. The yeastGemMap: A process diagram to assist yeast systems-metabolic studies. Biotechnology and Bioengineering. 18 (12):4800-4814. 2021. https://doi.org/10.1002/bit.27943. Online ISSN: 10970290.
(104) Perez-Cadena R., Espinosa-Solares T., Medina-Moreno S.A., Martinez A., Lizardi-Jimenez M.A., Tellez-Jurado A. Effect of the age of Opuntia ficus-indica cladodes on the release of simple sugars. Biocatalysis and Agricultural Biotechnology. 33, 10 2021. https://doi.org/10.1016/j.bcab.2021.102010. ISSN: 18788181.
(103) Cano-Díaz G.S., Rosas-Aburto A., Vivaldo-Lima E., Flores-Santos L., Vega-Hernández M.A., Hernández-Luna M.G., Martinez A. Determination of the Composition of Lignocellulosic Biomasses from Combined Analyses of Thermal, Spectroscopic, and Wet Chemical Methods. Industrial & Engineering Chemical Research. 60(9):3502-3515. 2021. https://dx.doi.org/10.1021/acs.iecr.0c05243. Print Edition ISSN: 0888-5885. Web Edition ISSN: 15205045.
(102) Vega-Hernández M.Á., Cano-Díaz G.S Vivaldo-Lima E, Rosas-Aburto A, Hernández-Luna M.G. Martinez A., Palacios-Alquisira J, Mohammadi Y., Penlidis A. A Review on the Synthesis, Characterization, and Modeling of Polymer Grafting. Processes. 9(375): 1-94. 2021. https://doi.org/10.3390/pr9020375. ISSN: 22279717.
(101) Werlang, E., Sierra-Ibarra, E., de Farias Neves, F., Julich, J., Martinez, A., de Cassia de Souza Schneider, R. D-lactate production from spirulina (Arthrospira platensis) biomass using lactogenic Escherichia coli. Bioresource Technology Reports. 12(100598):1-6. 2020. https://doi.org/10.1016/j.biteb.2020.100598. Electronic ISSN: 2589014X.
(100) Sierra-Ibarra, E., Leal-Reyes, L.J., Huerta-Beristain G., Hernández-Orihuela, A.L., Gosset, G., Martínez-Antonio, A., Martinez, A. Limited oxygen conditions as an approach to scale‑up and improve D and L‑lactic acid production in mineral media and avocado seed hydrolysates with metabolically engineered Escherichia coli. Bioprocess and Biosystems Engineering. 44(2):379-389. 2021. https://doi.org/10.1007/s00449-020-02450-1. Electronic ISSN 16157605, Print ISSN 16157591.
(99) Werlang, E.B., Julich, J., Muller, M.V.G., Neves, F.F., Sierra-Ibarra, E., Martinez, A., Schneider, R.C.S. Bioethanol from hydrolyzed Spirulina (Arthrospira platensis) biomass using ethanologenic bacteria. Bioresources and Bioprocessing. 7:27. 2020. https://doi.org/10.1186/s40643-020-00315-9. Electronic ISSN: 21974365.
(98) Martínez LM, Martinez A, Gosset G. Production of melanins with recombinant microorganisms. Frontiers in Bioengineering and Biotechnology. 7:285. 2019. https://doi.org/10.3389/fbioe.2019.00285. Electronic ISSN 22964185.
(97) Fernández-Sandoval Marco T., Juvencio Galíndez-Mayer, Francisco Bolívar, Guillermo Gosset, Octavio T. Ramírez, Alfredo Martinez. Xylose-glucose co-fermentation to ethanol by Escherichia coli strain MS04 using single- and two-stage continuous cultures under micro-aerated conditions. Microbial Cell Factories. 18:145. 2019. https://doi.org/10.1186/s12934-019-1191-0. Electronic ISNN 14752859.
(96) Caspeta Luis, Coronel Jesús, Montes de Oca Arturo, Eduardo Abarca, Lidia González, Martinez Alfredo. 2019. Engineering high-gravity fermentations for ethanol production at elevated-temperature with Saccharomyces cerevisiae. Biotechnology and Bioengineering. 116:2587-2597. 2019. https://doi.org/10.1002/bit.27103. Online ISSN: 10970290.
(95) Juan-Carlos Sigala, Quiroz Lucy, Arteaga Eduardo, Olivares Roberto, Lara Alvaro R. Martínez Alfredo. 2019. Physiological and transcriptional comparison of acetate catabolism between Acinetobacter schindleri ACE and Escherichia coli JM101. FEMS Microbiology Letters. 366 (12):(1-9) fnz151 . https://doi.org/10.1093/femsle/fnz151. ISSN 0378-1097. Electronic ISSN 15746968.
(94) Salcedo-Vite Karina, Sigala Juan Carlos, Segura Daniel, Gosset Guillermo, Martinez Alfredo. 2019 Acinetobacter baylyi ADP1 growth performance and lipid accumulation on different carbon sources. Applied Microbiology and Biotechnology, 103 (15):6217-6229. https://doi.org/10.1007/s00253-019-09910-z. Electronic ISNN 14320614. Print ISSN 01757598.
(93) Carreón-Rodríguez Ofelia E., Gutiérrez-Ríos Rosa María, Acosta José L., Martinez Alfredo, Cevallos Miguel A. 2019. Phenotypic and genomic analysis of Zymomonas mobilis ZM4 mutants with enhanced ethanol tolerance. Biotechnology Reports, 23(e00328): 1-9. https://doi.org/10.1016/j.btre.2019.e00328. Electronic ISSN 2215017X.
(92) Fragoso-Jiménez JC., Baert J.; Nguyen T.M., Liu W., Sassi H., Goormaghtigh F., Van Melderen L., Gaytán P., Hernández-Chávez G., Martinez A., Delvigne F., Gosset G. 2019. Growth-dependent recombinant product formation kinetics can be reproduced through engineering of glucose transport and is prone to phenotypic heterogeneity. Microbial Cell Factories. 18(26):1-16, 2019. https://doi.org/10.1186/s12934-019-1073-5. Electronic ISSN 14752859.
(91) Hernández-Chávez, G., Martinez, A., Gosset, G. Metabolic engineering strategies for caffeic acid production in Escherichia coli. Electronic Journal of Biotechnology, 38:19-26. 2019. https://doi.org/10.1016/j.ejbt.2018.12.004. Electronic ISSN 07173458.
(90) Arana-Cuenca, A., Tovar-Ximenez, X., Favela-Torres, E., Perraud-Gaime, I., Gonzalez-Becerra, A.E., Martinez, A., Moss-Acosta, C.L., Mercado-Flores, Y., Tellez-Jurado, A. 2019. Use of water hyacinth as a substrate for the production of filamentous fungal hydrolytic enzymes in solid-state fermentation. 3 Biotech, 9(21): 1-9. https://doi.org/10.1007/s13205-018-1529-z. Electronic ISSN 21905738. ISSN impreso 2190572X. ISSN electrónico 2190572X.
(89) Parra-Ramírez, D. Martinez, A. Cardona, C.A. 2019. Lactic acid production from glucose and xylose using the lactogenic Escherichia coli strain JU15: Experiments and techno-economic results Bioresource Technology, 273, 86-92. https://doi.org/10.1016/j.biortech.2018.10.061. Print ISSN: 09608524
(88) Parra-Ramírez D., Martinez A., Cardona C.A. Technical and economic potential evaluation of the strain Escherichia coli MS04 in the ethanol production from glucose and xylose. Biochemical Engineering Journal. 140:123-129. (2018). https://doi.org/10.1016/j.bej.2018.09.015. ISSN: 1369703X.
(87) Serna-Loaiza S., Martinez A. Pisarenko Y., Cardona-Alzate C.A. 2018. Integral use of plants and their residues: the case of cocoyam (Xanthosoma sagittifolium) conversion through biorefineries at small scale. Environmental Science and Pollution Research. 25(36):35949-35959. https://doi.org/10.1007/s11356-018-2313-7. Online ISSN 16147499. Print ISSN 09441344.
(86) Salas-Navarrete C., Hernández-Chávez G., Flores N., Martínez L.M., Martinez A., Bolívar F., Barona-Gomez F., Gosset G. Increasing pinosylvin production in Escherichia coli by reducing the expression level of the gene fabI-encoded enoyl-acyl Carrier protein reductase. Electronic Journal of Biotechnology 33:11-16. (2018). https://doi.org/10.1016/j.ejbt.2018.03.001. Electronic ISSN: 07173458.

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx